简化“六字诀”联合体外膈肌起搏对COPD稳定期患者SGRQ评分、6MWD及生活质量的影响  

The effects of simplified six-word formula combined with extracorporeal phrenic pace-making on SGRQ score,6MWD and quality of life of patients with COPD stable period

作　　者：方英[1] 方群[1] 王世强[1] 徐一凯 李琴[1] 陈梅 FANG Ying;FANG Qun;WANG Shi-qiang;XU Yi-kai;LI Qin;CHEN Mei(Department of Respiratory Medicine,the Third Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine,Hangzhou 310000,Zhejiang,China)

机构地区：[1]浙江中医药大学附属第三医院呼吸内科,浙江杭州310000

出　　处：《广东医学》2022年第12期1551-1556,共6页Guangdong Medical Journal

基　　金：浙江省中医药科技计划项目(2020ZB133)。

摘　　要：目的探究简化“六字诀”联合体外膈肌起搏对慢性阻塞性肺疾病(COPD)稳定期患者圣·乔治呼吸问卷(SGRQ)评分、6 min步行距离(6MWD)及生活质量的影响。方法选取120例COPD稳定期患者,按照随机数字表法分为4组:基础组(基础治疗)、六字诀组(基础治疗联合简化“六字诀”功法训练)、膈肌组(基础治疗联合体外膈肌起搏治疗)、联合组(基础治疗、简化“六字诀”功法训练联合体外膈肌起搏治疗),每组30例。比较4组患者治疗前后中医症候积分、COPD多因素分级系统(BODE)[体质指数(BMI)、第1秒用力呼气容积占预计值百分比(FEV1%)、呼吸困难指数(mMRC)、6MWD]、SGRQ评分以及半年内急性加重例数、住院次数、住院时间。结果4组治疗前BODE指数、中医症候积分、SGRQ评分比较差异无统计学意义(P>0.05)。治疗后,4组BODE指数、中医症候积分、SGRQ评分较治疗前均明显降低(P<0.05),且联合组<膈肌组<六字诀组<基础组(P<0.05)。治疗后4组半年内住院次数以及住院时间,基础组、六字诀组、膈肌组、联合组依次降低(P<0.05)。结论简化“六字诀”联合体外膈肌起搏治疗COPD稳定期患者,可有效改善患者临床症状及呼吸功能、缓解呼吸困难程度,增加运动耐力,降低住院率。Objective To evaluate the effects of simplified six-word formula combined with extracorporeal phrenic pace-making on ST-George Respiratory Questionnaire(SGRQ)score,6-minute walking distance(6MWD)and quality of life of patients with chronic obstructive pulmonary disease(COPD)stable period.Methods 120 COPD stable period patients were selected from the department of respiratory medicine,the Third Hospital affiliated to Zhejiang University of traditional Chinese medicine.They were divided into 4 groups according to the random number table,the basic group(basic treatment),the six-word formula group(basic therapy combined with simplified six-word formula skill training),the diaphragm group(basic therapy combined with external diaphragm pacing treatment),and the combination group(basic therapy,simplified six-word formula skill training combined with external diaphragm pacing treatment),with 30 cases in each group.Before and after treatment,the TCM symptom score,COPD multi factor classification system(BODE)index,including body mass index(BMI),first second forced expiratory volume as a percentage of predicted value(FEV1%),modified British medical research council dyspnea index(mMRC)and 6MWD,SGRQ score,the number of people acute aggravation within half an year,the number of hospitalizations and the average number of days hospitalization were compared among the four groups.Results There was no significant difference in BODE index,TCM symptom score,or the SGRQ score among the four groups before treatment(P>0.05);after treatment,the BODE index,TCM symptom score,the SGRQ score of the four groups were significantly lower than those before treatment(P<0.05);which was significantly the lowest in the combination group,and followed with the diaphragm group,the six-word formula group and the basic group(P<0.05).After treatment,the number of hospital stay and the average length of stay in the four groups within half an year decreased in turn in the basic group,the six character formula group,the diaphragm group and the combination gr

关 键 词：慢性阻塞性肺疾病 简化“六字诀” 体外膈肌起搏 中医症候积分 呼吸困难指数 

分 类 号：R563.9[医药卫生—呼吸系统] R493[医药卫生—内科学]