微量冷冻睾丸精子复苏后行卵胞浆内单精子显微注射的临床结局  

Clinical outcomes of intracytoplasmic sperm injection with micro amount of frozen-thawed testicular sperm

作　　者：周龙萍 ZHOU Longping(Department of Reproduction and Genetics,Ganzhou Maternal and Child Health Care,Jiangxi Province,Ganzhou341000,China)

机构地区：[1]江西省赣州市妇幼保健院生殖与遗传科,江西赣州341000

出　　处：《中国当代医药》2023年第2期114-116,共3页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202212355)。

摘　　要：目的探讨微量冷冻睾丸精子复苏后行卵胞浆内单精子显微注射(ICSI)的临床结局。方法选取2017年1月至2021年12月于赣州市妇幼保健院接受睾丸组织活检且证实存在存活精子的无精症患者的113个周期资料,依据精子保存方式不同分为A组(61个周期)和B组(52个周期)。A组采用微量冷冻睾丸精子,B组采用新鲜精子。比较两组患者的妊娠结局以及新生儿情况。结果两组患者的获卵数、正常卵成熟率、正常受精率、优质胚胎率、囊胚形成率、妊娠率以及流产率比较,差异均无统计学意义(P>0.05)。两组新生儿的性别、体重、身长及畸形情况比较,差异无统计学意义(P>0.05)。结论微量冷冻睾丸精子复苏后行卵胞浆内单精子显微注射在保证临床结局良好同时减少反复、不必要的对卵巢与睾丸的刺激。Objective To investigate the clinical outcomes of intracytoplasmic sperm injection(ICSI)with micro amount of frozen-thawed testicular sperm.Methods From January 2017 to December 2021,113 cycles of anspermia patients who received testicular tissue biopsy in Ganzhou Maternal and Child Health Hospital and confirmed the existence of viable sperm were selected and divided into group A(61 cycles)and group B(52 cycles)according to different storage methods.Group A used trace frozen testicular sperm,group B used fresh sperm.The pregnancy outcome and neonatal condition of the two groups were compared.Results There were no significant differences in the number of eggs obtained,normal egg maturation rate,normal fertilization rate,high-quality embryo rate,blastocyst formation rate,pregnancy rate and abortion rate between two groups(P>0.05).There were no significant differences in gender,body weight,body length and deformity between the two groups(P>0.05).Conclusion ICSI with micro amount of frozen-thawed testicular sperm can ensure good clinical outcomes and reduce repeated or unnecessary stimulation to the ovary and testis.

关 键 词：无精症 微量冷冻睾丸精子 卵胞浆内单精子显微注射 临床结局 

分 类 号：R169[医药卫生—公共卫生与预防医学]