迷迭香酸磁性分子印迹聚合物的合成及应用  

Synthesis and Application of Rosmarinic Acid Magnetic Molecularly Imprinted Polymers

作　　者：张伟[1] 韩祎陟 罗云敬[1] 邹明强[2] ZHANG Wei;HAN Yizhi;LUO Yunjing;ZOU Mingqiang(Beijing Key Laboratory of environmental and viral oncology,Department of environment and life,Beijing University of technology,Beijing 100124;China Academy of inspection and quarantine,Beijing 100123;Hohhot international travel health care center,Hohhot 010020)

机构地区：[1]北京工业大学环境与生命学部,环境与病毒肿瘤学北京市重点实验室,北京100124 [2]中国检验检疫科学研究院,北京100123 [3]呼和浩特国际旅行卫生保健中心,呼和浩特010020

出　　处：《分析科学学报》2022年第6期723-728,共6页Journal of Analytical Science

基　　金：市场监管典型国产科学仪器验评与推广(Z201100009319001);国家重点研发计划(NO.2016YFF0203802)。

摘　　要：本文使用磁性分子印迹技术,合成了同时具有超顺磁性和吸附选择性的迷迭香酸磁性分子印迹聚合物(R-MMIPs)。在外加磁场的作用下,R-MMIPs可以快速提取分离复杂基质中的迷迭香酸。采用扫描电子显微镜(SEM)、傅里叶变换红外光谱(FT-IR)、透射电子显微镜(TEM)和磁强振动计(VSM)对纳米材料的微观结构进行表征。通过吸附实验评价其结合能力和特异性,其最大吸附量为8.68 mg/g。此外,R-MMIPs成功地实现了从实际样品中提取和分离迷迭香酸,加标回收率为88.1%~107.5%。本方法具有操作简便、吸附速度快、选择性高等优点,适用于复杂基质中迷迭香酸的快速选择性分离。In this study,rosmarinic acid magnetic molecular imprinting polymers(R-MMIPs)with both superparamagnetic and adsorption selectivity were synthesized using magnetic molecular imprinting technology.Under an applied magnetic field,R-MMIPs can rapidly extract and separate rosmarinic acid from complex matrices.The microstructure of the nanomaterials was characterized by scanning electron microscope(SEM),fourier transform infrared spectroscopy(FT-IR),transmission electron microscope(TEM)and magnetic intensity vibrometer(VSM).The binding capacity and specificity were evaluated by adsorption experiment.The maximum adsorption capacity was 8.68 mg/g.In addition,RosA was successfully extracted and separated from actual samples,and the recovery was 88.1%-107.5%.The method has the advantages of simple operation,fast adsorption,and high selectivity.It is suitable for the rapid and selective separation of RosA in a complex matrix.

关 键 词：迷迭香酸 分子印迹技术 磁性分子印迹聚合物 

分 类 号：O657.72[理学—分析化学]