High-efficiency 3D cell spheroid formation via the inertial focusing effect in rotating droplets  

作　　者：Tan Tang Peipei Zhang Yanran Wei Hongxing Jia Lin Feng Ye Xu 

机构地区：[1]School of Mechanical Engineering and Automation,Beihang University,Beijing 100191,China [2]Center of Soft Matter Physics and Its Applications,Beihang University,Beijing 100191,China

出　　处：《Bio-Design and Manufacturing》2023年第1期90-97,共8页生物设计与制造（英文）

基　　金：the Fundamental Research Funds for the Central Universities(Nos.JKF-YG20-B008 and YWF-19-BJ-J-132);the National Natural Science Foundation of China(Nos.11674019 and 12072010)for the financial support;partially supported by Yunnan Baiyao Group Co.Ltd.

摘　　要：The three-dimensional(3D)spheroid culture has been widely used as an important tool in biological research.Although several techniques have been established to prepare cell spheroids,fast and controllable production remains one of the major challenges.In this study,a simple but efficient method utilizing the inertial focusing effect in rotating hanging droplets is demonstrated for the rapid and controllable production of cell spheroids.

关 键 词：ROTATING effect utilizing 

分 类 号：R318[医药卫生—生物医学工程]