含碘中药治疗甲状腺疾病的作用机制探讨  

Mechanism of iodine-containing traditional Chinese medicine for thyroid diseases

作　　者：杨涛 马思懿 姜敏[1] YANG Tao;MA Si-yi;JIANG Min(Department of Traditional Chinese Medicine,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038)

机构地区：[1]首都医科大学附属北京世纪坛医院中医科,北京100038

出　　处：《中南药学》2022年第12期2837-2842,共6页Central South Pharmacy

基　　金：国家中医药管理局基本中医药循证能力建设项目(No.2019XZZX-JB004);国家中医药管理局、国家卫生计生委、中央军委后勤保障部卫生局“重大疑难疾病中西医临床协作能力建设项目”(No.国中医药医政发【2018】3号);北京市中医药科技发展资金项目(No.JJ-2020-57)

摘　　要：含碘中药治疗甲状腺疾病的历史已久,《肘后备急方》就有海藻、昆布治疗瘿病的记载,海藻玉壶汤、四海舒郁丸、消瘰丸等沿用至今的经典方剂均使用含碘中药。随着人们对疾病病理机制的深入认识,含碘中药应用于甲状腺疾病的治疗引起一定争议,如何合理使用含碘中药是亟待解决的问题。在“辨证论治”的指导下,结合现代药理学机制研究结果,可能是较为合理的途径。本文旨在梳理含碘中药在甲状腺疾病中的机制研究进展,为其进一步研究和临床应用提供参考。Iodine-containing traditional Chinese medicines have long been used for thyroid diseases.In the“Handbook of Prescriptions for Emergencies”,there are records of seaweed and kombu for goiter diseases,and classical prescriptions such as Seaweed Yuhu decoction,Sihai Shuyu pills and Xiaoluo pills all use iodine-containing traditional Chinese medicine till today.With deeper understanding of the pathological mechanism of the disease,the application of iodine-containing traditional Chinese medicines for thyroid diseases has caused some controversy,and the rational use of iodine-containing traditional Chinese medicine is also a problem.It may be a more reasonable way to combine the results of modern pharmacological study.This review aims to sort out the progress in the mechanism of iodine-containing traditional Chinese medicine for thyroid diseases and provide reference for further research and clinical application.

关 键 词：含碘中药 甲状腺疾病 瘿病 机制 

分 类 号：R259[医药卫生—中西医结合]