某新冠定点救治医院新型冠状病毒奥密克戎变异株环境污染调查  

Environmental contamination by SARS-CoV-2 Omicron variant in a designated COVID-19 treatment hospital

作　　者：王美霞 史庆丰 李娜 孙伟 占蒙娜 郎军涛 忻佳 周玮 李培 孟丽丽 刘文娟 王冲 沈隽霏 米宏霏 高晓东 胡必杰 潘珏[1,3] WANG Mei-xia;SHI Qing-feng;LI Na;SUN Wei;ZHAN Meng-na;LANG Jun-tao;XIN Jia;ZHOU Wei;LI Pei;MENG Li-li;LIU Wen-juan;WANG Chong;SHEN Jun-fei;MI Hong-fei;GAO Xiao-dong;HU Bi-jie;PAN Jue(Department of Healthcare-associated Infection Management,Zhongshan Hospital,Fudan University,Xiamen 361006,China;Department of Healthcare-associated Infection Management,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Infectious Diseases,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Pathology,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Nuclear Medicine,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Nursing,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Ultrasound,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Psychology,Zhongshan Hospital,Fudan University,Shanghai 200030,China;Department of Laboratory Medicine,Zhongshan Hospital,Fudan University,Shanghai 200030,China)

机构地区：[1]复旦大学附属中山医院(厦门)院感管理部,福建厦门361006 [2]复旦大学附属中山医院感染管理科,上海200030 [3]复旦大学附属中山医院感染病科,上海200030 [4]复旦大学附属中山医院病理科,上海200030 [5]复旦大学附属中山医院核医学科,上海200030 [6]复旦大学附属中山医院护理部,上海200030 [7]复旦大学附属中山医院超声科,上海200030 [8]复旦大学附属中山医院心理医学科,上海200030 [9]复旦大学附属中山医院检验科,上海200030

出　　处：《中国感染控制杂志》2023年第1期89-95,共7页Chinese Journal of Infection Control

基　　金：上海申康医院发展中心市级医院临床科技创新项目(SHDC22021315)。

摘　　要：目的评估新型冠状病毒奥密克戎变异株对病区公共环境及医务人员个人防护用品的污染情况。方法对某新冠定点救治医院病区公共区域、脱卸区域和个人防护用品进行采样,采用实时荧光定量聚合酶链反应(PCR)检测新型冠状病毒核酸并报告Ct值,分析个人防护用品新型冠状病毒阳性相关因素。结果共采集病区公共区域环境标本100份,病区公共区域环境新型冠状病毒核酸检测总阳性率为30.00%,脱卸区电梯地面、走廊公共区域地面、脱卸电梯按钮新型冠状病毒核酸检测阳性率最高,分别为60.00%、60.00%、40.00%。一脱区和二脱区新型冠状病毒核酸检出率分别为18.33%、1.67%。48.33%的工作人员个人防护用品检出新型冠状病毒核酸,其中外层鞋套鞋底、外层手套和防护服检出率最高,分别为35.00%、21.67%、8.33%。单因素分析结果显示医生岗位和高风险操作医务人员个人防护用品新型冠状病毒核酸检测阳性率高(均P<0.05)。结论新型冠状病毒奥密克戎变异株对病区公共环境、一脱区和个人防护用品可造成不同程度污染,做好个人防护和定期环境清洁消毒,可以降低医务人员感染风险。Objective To evaluate the contamination of public environment and medical staff’s personal protective equipment(PPE)by SARS-CoV-2 Omicron variant.Methods Public area,PPE removal area and PPE of a designated COVID-19 treatment hospital were sampled.Real time fluorescence quantitative polymerase chain reaction was adopted to detect SARS-CoV-2 nucleic acid and Ct value was reported.Factors related to positive SARS-CoV-2 nucleic acid results of PPE were analyzed.Results A total of 100 environmental specimens from ward public area were collected and the overall positive rate was 30.00%.Positive rates of elevator floor in PPE removal area(60.00%),corridor public area floor(60.00%),and the elevator button in PPE removal area(40.00%)were the highest.SARS-CoV-2 nucleic acid detection rates in the first-level and second-level PPE removal areas were 18.33%and 1.67%.SARS-CoV-2 nucleic acid was detected from 48.33%staff’s PPE,35.00%,21.67%and 8.33%of which were detected from soles of outer shoe covers,outer gloves and protective clothing.Univariate analysis showed that PPE of doctors and medical staff performing high-risk manipulation had high positive rate of nucleic acid(all P<0.05).Conclusion Omicron variant contaminated the ward public area,the first-level PPE removal area and PPE to different degrees.Personal protection as well as regular environmental cleaning and disinfection can reduce the infection risk of medical staff.

关 键 词：新型冠状病毒 奥密克戎变异株 环境污染 个人防护用品 

分 类 号：R181.32[医药卫生—流行病学]