运用Framingham评分探究体力活动与心血管疾病患病率相关性  

Using Framingham Risk Score to Explore the Association between Physical Activity and the Prevalence of Cardiovascular Disease

作　　者：曹岩鹏 CAO Yan-peng(College of Physical Education,Jimei University,Xiamen 361021,China)

机构地区：[1]集美大学体育学院,福建厦门361021

出　　处：《体育科学研究》2022年第6期70-77,86,共9页Sports Science Research

基　　金：教育部人文社科规划项目(20YJA890014);省科技厅创新战略研究项目(2020R0068)。

摘　　要：运用Framingham心血管风险评分探究体力活动与心血管疾病患病率间的相关性。选定对151名成年人进行问卷调查及生理生化指标测试,根据Framingham心血管分层方法(<10%、≥10%)将心血管患病风险划分为有风险组和无风险组,依据国际体力活动问卷(IPAQ)划分标准(<600、600≤X≤3000和>3000 MET-min/w)将体力活动划分为低(LPA)、中(MPA)、高(VPA)三种等级。采用独立样本T检验、秩和检验、单因素方差分析、卡方检验、一元线性回归分析等方法对调查结果进行统计学分析。结果:(1)无风险组体力活动水平显著高于风险组(P<0.05),随着心血管疾病患病风险的提高,体力活动水平在男女中均呈降低趋势(P<0.05);(2)男性血脂、血糖水平优于女性,表现为HDL-C、HbA1c、TC、LDL-C均低于女性(P<0.05),但男性拥有更高的心血管疾病患病风险(中位数:8%vs 6%);(3)不同体力活动水平组中心血管疾病患病率均存在显著差异(P<0.05),分别为LPA(18.2±13.5%)vs MPA(8.8±5.9%)vs VPA(5.8±3.6%);(4)一元线性回归分析显示体力活动量与心血管疾病患病率存在负相关(P<0.05),体力活动水平每上升1000 MET-min/w,男性心血管疾病患病风险降低8%,女性心血管疾病患病风险下降7%。结论:(1)体力活动水平越高,各项生理指标均呈良好趋势,心血管疾病患病风险显著降低;(2)体力活动水平与心血管疾病患病率存在“剂量-效应关系”,体力活动可以作为评定心血管疾病患病风险评价指标。To explore the association between physical activity and the prevalence of cardiovascular disease using the Framingham cardiovascular risk score.Methods:A total 151 subjects were divided into low,medium and high risk groups according to the Framingham cardiovascular risk layering method(<10%、10%≤X<20%and≥20%),each group was divided into categories of low(LPA),medium(MPA)and high(VPA)physicla activity level(<600、600≤X≤3000 and≥3000 MET min/w).The independent sample t test,rank sum test,oneway ANOVA,Chi square test and linear regression analysis were used to analyze the survey results.Results:(1)Physical activity level in the no risk group were significantly higher than those in the risk group,physical activity level decreased in both men and women as the risk of cardiovascular disease increased;(2)The serum lipids and blood glucose of men were higher than those of women,and the HDL-C,HbA1c,TC,and LDL-C were lower than those of women(P<0.05),men had a higher risk of cardiovascular disease(median:8%vs 6%);(3)There were significant differences in the prevalence of CVD among different physical activity groups(P<0.05),which were LPA(18.2±13.5%)vs MPA(8.8±5.9%)vs VPA(5.8±3.6%).(4)Linear regression analysis showed that there was a negative correlation between the amount of physical activity and the prevalence of cardiovascular disease(P<0.05).The risk of cardiovascular disease decreased by 8%in men and 7%in women for every 1000 MET min/w increase in physical activity level.Conclusions:(1)The higher the level of physical activity,the better the physiological and biochemical indexes,the lower cardiovascular disease risks;(2)There was a“dose-effect relationship”between the level of physical activity and the prevalence of cardiovascular disease,physical activity could be used as an indicator for the risk assessment of cardiovascular disease.

关 键 词：体力活动 Framingham心血管风险评分 心血管疾病患病率 健康效益 

分 类 号：G804.5[文化科学—运动人体科学]