呼气流量峰值监测在儿童哮喘管理中的作用研究  

Study on the role of peak expiratory flow monitoring in children’s asthma management

作　　者：孙雪梅 周高俊 金莹 Sun Xuemei;Zhou Gaojun;Jin Ying(Department of Pediatrics,Shunyi Women's and Children's Hospital of Beijing Children’s Hospital,Bejing 101300,China)

机构地区：[1]北京市顺义区妇幼保健院,北京儿童医院顺义妇儿医院儿科,101300

出　　处：《北京医学》2022年第11期1011-1014,共4页Beijing Medical Journal

基　　金：北京儿童医院顺义妇儿医院妇幼健康基金(FYJK-201704)。

摘　　要：目的探讨呼气流量峰值(peak expiratory flow,PEF)监测在儿童哮喘管理中的作用,为优化哮喘患儿的临床管理提供科学依据。方法选取2017年12月至2018年12月北京市顺义区妇幼保健院儿科门诊就诊的40名哮喘患儿,根据随机数字表法随机分为实验组和对照组,每组20例。实验组进行PEF监测,实验组和对照组均进行6个月的随访观察。记录并比较2组儿童基线期、随访3个月和6个月时肺功能[第1秒用力呼气容积/用力肺活量(forced expiratory volume in first second/forced vital capacity,FEV1/FVC)]、儿童哮喘控制测试评分(childhood asthma control test,C-ACT)和治疗级别。结果40例患儿中,男22例,女18例;年龄6~12岁,平均(9.1±2.0)岁;病程2~12个月,平均(7.2±2.0)个月。两组在性别、年龄、基线期的肺功能和C-ACT评分和治疗级别的比较,差异均无统计学意义(P>0.05)。随访3个月时,实验组肺功能和C-ACT评分均高于对照组[(86.0±3.0)比(81.4±7.4)和(22.5±1.1)分比(20.4±1.8)分],治疗级别低于对照组[(3.6±0.5)比(4.0±0.2)],差异均有统计学意义(P<0.05)。随访6个月时,实验组肺功能和C-ACT评分均高于对照组[(86.0±3.2)比(81.0±7.1)和(22.5±1.2)分比(20.8±1.2)分],治疗级别低于对照组[(3.5±0.5)比(3.9±0.4)],差异均有统计学意义(P<0.05)。结论PEF监测可提高哮喘患儿规范化治疗效果和生活质量,达到长期控制的目标。该法简便易行,值得临床推广。Objective To explore the role of peak expiratory flow(PEF)monitoring in children’s asthma management,and to provide scientific basis for optimizing clinical management of children with asthma.Methods A total of40 children with asthma treated in the Outpatient Department of Pediatrics Shunyi Women’s and Children’s Hospital of Beijing Children’s Hospital from December 2017 to December 2018 were selected,and were randomly divided into experimental group and control group according to the random number table method,with 20 cases in each group.The experimental group was monitored by PEF,both the two groups were followed up for 6 months.The pulmonary function[forced expiratory volume in the first second/forced vital capacity(FEV1/FVC)],children asthma control test score(C-ACT)and treatment level were recorded and compared between the two groups at baseline,3 months and 6 months follow-up.Results Among the 40 children,22 were males and 18 were females,the age ranged from 6 to 12 years old,with an average age of(9.1±2.0)years.The course of the disease ranged from 2 to 12 months,with an average of(7.2±2.0)months.There were no significant difference in gender,average age,pulmonary function,C-ACT score and treatment level at baseline between the two groups(P>0.05).After 3 months of follow-up,the pulmonary function and C-ACT score of the experimental group were higher than those of the control group[(86.0±3.0)vs.(81.4±7.4),(22.5±1.1)score vs.(20.4±1.8)score],and the treatment level was lower than that of the control group[(3.6±0.5)vs.(4.0±0.2)],the differences were statistically significant(P<0.05).After6 months of follow-up,the pulmonary function and C-ACT score of the experimental group were higher than those of the control group[(86.0±3.2)vs.(81.0±7.1),(22.5±1.2)score vs.(20.8±1.2)score],and the treatment level was lower than that of the control group[(3.5±0.5)vs.(3.9±0.4)],the differences were statistically significant(P<0.05).Conclusions PEF monitoring can improve the standardized treatment effect

关 键 词：呼气流量峰值 监测 哮喘 儿童 

分 类 号：R725.6[医药卫生—儿科]