深圳市龙华区老年人骨密度数据库建立与骨质疏松症相关因素研究  

Establishment of bone mineral density database of the elderly in Longhua District and Study on related factors of osteoporosis

作　　者：张灿 ZHANG Can(Shenzhen Longhua District People's Hospital,Shenzhen 518109,China)

机构地区：[1]广东省深圳市龙华区人民医院,518109

出　　处：《中国老年保健医学》2022年第6期91-94,共4页Chinese Journal of Geriatric Care

摘　　要：目的研究深圳市龙华区老年人骨密度数据库建立与骨质疏松症相关因素。方法选出本辖区2021年1月至12月行健康体检的60岁以上老年人240例,均采用定量CT测量法(QCT)测定骨密度值,并建立骨密度数据库;骨密度绝对值≤80mg/cm^(3)则诊断为骨质疏松症,计算骨质疏松症的发生率。根据是否发生骨质疏松症,将老年人分为骨质疏松症组与非骨质疏松症组,对比两组基本资料(性别、年龄、体质指数、体表面积、腹部脂肪、糖尿病史、甲状旁腺激素、降钙素、血压、胰岛素水平、血钙、血磷和骨密度)的差异性,运用Logistic分析法分析骨质疏松症的相关因素。结果240例老年人中,骨密度值最小为57mg/cm^(3),最大为123mg/cm^(3),平均(92.45±3.84)mg/cm^(3),其中骨密度绝对值≤80mg/cm^(3)共87例,骨质疏松症发生率为36.25%。骨质疏松症组87例,非骨质疏松症组153例。两组的性别、年龄、体质指数、体表面积、腹部脂肪、糖尿病史、甲状旁腺激素、降钙素、胰岛素抵抗指数、骨密度对比,差异均有统计学意义(P<0.05)。两组的收缩压、舒张压、血钙、血磷对比,差异均无统计学意义(P>0.05)。Logistic多因素分析结果显示,性别(男)、降钙素(≥15pmol/ml)、骨密度(≥80mg/cm^(3))均是骨质疏松症的保护因素,年龄(≥75岁)、体质指数(≥23kg/m^(2))、体表面积(≥1.7m^(2))、腹部脂肪(≥28%)、糖尿病史(有)、甲状旁腺激素(≥70pg/ml)、胰岛素抵抗指数(≥2.69)均是骨质疏松症的危险因素。结论导致龙华区老年人发生骨质疏松症的相关因素较多,应采取相关措施予以消除,以降低发生率;同时应建立骨密度数据库,以了解老年人的骨质健康水平,便于辖区内老年人健康状况的监控。Objective To study the establishment of bone mineral density database of the elderly in Longhua District and the related factors of osteoporosis.Methods 240 elderly people over 60 years old who underwent physical examination from January 2021 to December 2021 were selected.The bone mineral density was measured by quantitative CT(QCT)and the bone mineral density database was established.The absolute value of bone mineral density≤80 mg/cm^(3) was diagnosed as osteoporosis,and the incidence of osteoporosis was calculated.According to the occurrence of osteoporosis,the elderly were divided into osteoporosis group and non osteoporosis group.The differences of the basic data(sex,age,body mass index,body surface area,abdominal fat,history of diabetes,parathyroid hormone,calcitonin,blood pressure,insulin level,blood calcium,blood phosphorus and bone mineral density)between the two groups were compared,and the related factors of osteoporosis were analyzed by logistic analysis.Results Among the 240 elderly,the minimum bone mineral density was 57 mg/cm^(3),the maximum was 123 mg/cm^(3),and the average was(92.45±3.84)mg/cm^(3).Among them,87 cases had an absolute value of bone mineral density≤80 mg/cm^(3).The incidence of osteoporosis was 36.25%.There were 87 cases in osteoporosis group and 153 cases in non osteoporosis group.There were significant differences in sex,age,body mass index,body surface area,abdominal fat,history of diabetes,parathyroid hormone,calcitonin,insulin resistance index and bone mineral density between the two groups(P<0.05).There was no significant difference in systolic blood pressure,diastolic blood pressure,blood calcium and blood phosphorus between the two groups(P>0.05).Logistic multivariate analysis showed that gender(male),calcitonin(≥15 pmol/ml)and bone mineral density(≥80 mg/cm^(3))were all protective factors of osteoporosis,age(≥75 years),body mass index(≥23 kg/m^(2))、Body surface area(≥1.7 m^(2))、Abdominal fat(≥28%),history of diabetes(yes),parathyroid hormone(≥70 pg/m

关 键 词：龙华区 老年人 骨密度 数据库建立 骨质疏松症 相关因素 

分 类 号：R580[医药卫生—内分泌]