血小板及其衍生物的保存方案和应用进展  

Preservation protocols and application progress of platelets and their derivatives

作　　者：潘宗岱[1] 薛静 孙士鹏[1] 刘贵建[1] 苗翠华[1] 杨美慧 PAN Zongdai;XUE Jing;SUN Shipeng;LIU Guijian;MIAO Cuihua;YANG Meihui(Department of Clinical Laboratory,Guang'anmen Hospital China Academy of Chinese Medical Sciences,Beijing,100053,China)

机构地区：[1]中国中医科学院广安门医院检验科,北京100053

出　　处：《临床血液学杂志》2022年第12期900-904,共5页Journal of Clinical Hematology

摘　　要：血小板不仅在止血、凝血中起着重要作用,而且随着研究的深入发现血小板的成分和衍生物还可以应用于疾病的诊断和治疗,在医美方面也有着广泛的应用。随着血小板研究价值的升高,血小板的保存方式也越来越得到重视。本文总结了几种主要的血小板保存方式的特点,包括短期保存(5 d)、中短期的保存(3周)、长期保存(多年)和成分保存。除短期保存外,其余保存方式还缺乏统一的标准,但随着研究的深入和临床应用,血小板保存需要标准化、自动化、简便化。选择更为合适且经济的保存方式进行成分保存也会成为趋势。Platelets play an important role in hemostasis and coagulation. More and more study found that the components and derivatives of platelets can be used in the diagnosis and treatment of diseases, and they also have broad applications in medical aesthetics. The preservation of platelets showed a critical role in the research and clinical application of platelets. Now, the characteristics of several main platelet preservation methods are summarized: short-term preservation(5 days), medium and short-term preservation(3 weeks), long-term preservation(many years) and component preservation ways. Except for short-term preservation, other preservation methods still lack unified standards. With the deepening of research and clinical application, platelet preservation needs to be standardized, automated and simplified. It will also become a trend to choose a more appropriate and economical way to preserve platelets components.

关 键 词：血小板 成分保存 冻干保存 富血小板血浆 血小板miRNA 

分 类 号：R457.1[医药卫生—治疗学]