基于辨机论治辨治成人多囊肾经验  

Experience in treating autosomal dominant polycystic kidney disease based on the theory of mechanism differentiation and treatment

作　　者：韩宜臻 王耀献[2] 陶嘉茵 王珍[1] HAN Yi-zhen;WANG Yao-xian;TAO Jia-yin;WANG Zhen(Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学东直门医院,北京100700 [2]北京中医药大学,北京100029

出　　处：《中华中医药杂志》2022年第12期7174-7177,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：重大新药创制科技重大专项(No.2017ZX09304019);国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄学者-国家中医药领军人才支持计划)(No.国中医药人教发[2018]12号)。

摘　　要：王耀献教授结合临床经验,基于辨机论治治疗成人多囊肾,总结该病以“饮停痰注,肾络癥瘕”为体质病机,“肝郁气滞,湿热内蕴,脾肾阳虚,阴虚阳亢”为证候病机,“肾用失司,浊毒内停”为衍生病机,并以证候病机为辨证要点,以疏肝解郁、清热祛湿、补肾健脾、平调阴阳为治疗原则,提出分期论治,将该病分为早期、晚期治疗,早期应以补益脾肾、疏利气机、清热化饮为法,晚期应以固本澄源、通畅三焦、化瘀排浊为法,以期提高临床疗效。Based on years of clinical experience,professor WANG Yao-xian uses mechanism differentiation theory to treat autosomal dominant polycystic kidney disease(ADPKD).According to the theory,phlegm and fluid retention and kidney collateral damage due to blood stasis and abdominal mass'is the physical mechanism,'accumulation disease with syndrome of liver depression and qi stagnation,and internal retention of damp-heat,and yang deficiency of spleen and kidney,and hyperactivity of yang due to yin deficiency"is the syndrome mechanism.Turbidity toxin in the body and the kidney is disable'is the derivative mechanism.The syndrome mechanism is the core syndrome differentiation element.Dispersing stagnated liver qi for relieving qi stagnation,and clearing heat and promoting diuresis,and nourishing spleen and kidney,and coordinating yin and yang are therapeutic principles.According to the course of disease,treatments are also formulated differently focused on different emphasis,in orderto improvethetherapeutic effect.

关 键 词：多囊肾 辨机论治 经验总结 分期论治 证候病机 

分 类 号：R277.5[医药卫生—中医学]