急性缺血性脑卒中FLAIR高信号血管征与SWI突出血管征的影响因素及其相关性研究  

Influence factors and correlation of hyperintense vessel sign on FLAIR and prominent vessel sign on SWI in patients with acute ischemic stroke

作　　者：陈妙玲[1] 梁满球[1] 邹玉坚[1] 肖利华[1] 黄翔[1] 莫少芬[1] 张转南 CHEN Miaoling;LIANG Manqiu;ZOU Yujian;XIAO Lihua;HUANG Xiang;MO Shaofen;ZHANG Zhuannan(Department of Radiology,Dongguan People’s Hospital,Dongguan 523000,China)

机构地区：[1]广东省东莞市人民医院放射科,广东东莞523000

出　　处：《中国中西医结合影像学杂志》2023年第1期21-26,共6页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：广东省东莞市社会科技发展(一般)项目(201950715001845)。

摘　　要：目的:探讨急性缺血性脑卒中(AIS)FLAIR高信号血管征(HVS)与SWI突出血管征(PVS)的影响因素及其相关性。方法:回顾性收集93例单侧大脑中动脉供血区AIS患者的临床及影像资料。采用改良Alberta卒中项目早期CT评分(ASPECTS)对HVS、PVS进行评分及分级。HVS评分、PVS评分与临床变量的相关性行Spearman相关性分析;采用Fisher确切概率法比较HVS分级、PVS分级与血管狭窄部位、狭窄程度的关系;HVS评分与PVS评分之间的相关性行Spearman相关性分析。结果:HVS评分、PVS评分均与基线美国国立卫生研究院卒中量表(NIHSS)评分呈正相关(r=0.377,0.490;均P<0.001),与CT评分(DWI-ASPECTS)呈负相关(r=-0.543,-0.672;均P<0.001)。HVS分级、PVS分级与血管狭窄部位、血管狭窄程度呈线性相关。HVS评分与PVS评分呈明显正相关(r=0.859,P<0.001)。结论:HVS分级、PVS分级越高,提示血管狭窄程度越重、越靠近颅内动脉近心端,与DWI-ASPECTS、基线NIHSS评分有一定的相关性。HVS评分、PVS评分具有较好的一致性,可能反映AIS期间不同但相互关联的脑血流动力学改变。Objective:To investigate the influencing factors and correlation of hyperintense vessel sign(HVS)on FLAIR and prominent vessel sign(PVS)on SWI in patients with acute ischemic stroke(AIS).Methods:The clinical and imaging data of 93 patients with AIS of unilateral middle cerebral artery were collected retrospectively.HVS and PVS were scored and graded by the modified Alberta Stroke Project Early CT Score(ASPECTS).Spearman correlation analysis was used to analyze the correlation between HVS score,PVS score and clinical variables;Fisher’s exact probability method was used to compare the relationship between HVS grade,PVS grade and the location and degree of vascular stenosis.Spearman correlation analysis was used to analyze the correlation between HVS score and PVS score.Results:HVS score and PVS score were positively correlated with the baseline National Institutes of Health Stroke Scale(NIHSS)score(r=0.377,0.490,both P<0.001),negatively correlated with DWI-ASPECTS(r=-0.543,-0.672,both P<0.001).HVS grade and PVS grade showed a linear correlation with the location and degree of vascular stenosis.HVS score was significantly positively correlated with PVS score(r=0.859,P<0.001).Conclusions:The higher the HVS grade and PVS grade,the more severe the stenosis degree and the closer to the intracranial artery proximal to the heart,and there is a certain correlation with DWI-ASPECTS and the baseline NIHSS score.HVS score and PVS score have a good consistency and may indicate the cerebral hemodynamic changes during AIS are different but interrelated.

关 键 词：卒中 液体衰减反转恢复序列 高信号血管征 磁敏感成像 突出血管征 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.3[医药卫生—诊断学]