小儿肾脏疾病肾活检病理诊断研究  

Pathological diagnosis study of renal biopsy in children with renal diseases

作　　者：齐美娇 QI Mei-jiao(Department of Pathology,Tianjin Children's Hospital/Tianjin University Children's Hospital,Tianjin 300400,China)

机构地区：[1]天津市儿童医院/天津大学儿童医院病理科,天津300400

出　　处：《中国城乡企业卫生》2022年第12期3-5,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目的分析小儿肾脏疾病肾活检病理诊断价值,为肾脏疾病患儿的临床诊断提供帮助。方法在2021年1月—2022年6月天津市儿童医院治疗的小儿肾脏疾病患儿中随机抽取50例设为观察组,另选择同时期在本市一综合医院接受治疗的成人肾脏疾病的50例患者设为对照组,均给予肾活检病理诊断,比较两组肾脏疾病类型、原发性肾小球疾病病理类型、继发性肾小球肾炎病理类型。结果观察组原发性肾小球疾病发生率为80.00%,高于对照组的60.00%,差异有统计学意义(P<0.05)。观察组IgA肾病发生率明显高于对照组,差异有统计学意义(P<0.05)。观察组系膜增生性病变、膜增生性肾炎、微小病变、膜性肾病发生率与对照组比较,差异无统计学意义(P>0.05)。观察组糖尿病肾病、高血压肾损伤发生率低于对照组,紫癜性肾炎发生率高于对照组,差异均有统计学意义(P<0.05);观察组狼疮性肾炎、淀粉样变性发生率与对照组比较,差异无统计学意义(P>0.05)。结论小儿肾脏疾病肾活检病理诊断对于肾脏疾病的诊断具有较高的准确率,与成人肾脏疾病差异明显,有利于分型的准确诊断,制订更加有效的疾病干预措施,值得临床推广应用。Objective To analyse the pathological diagnosis value of renal biopsy in children with renal diseases,in order to provide help for clinical diagnosis of children with renal diseases.Methods Fifty children with renal diseases treated in Tianjin Children’s Hospital from January 2021 to June 2022 were randomly selected as the observation group,and 50 adult patients with renal diseases admitted to a general hospital in the city at the same time were selected as the control group.All patients were given pathological diagnosis of renal biopsy.The renal diseases types,primary glomerular disease pathological types and secondary glomerulonephritis pathological types were compared between the two groups.Results The incidence of primary glomerular disease in the observation group was 80.00%,which was higher than that in the control group with 60.00%,and the difference was statistically significant(P<0.05).The incidence of IgA nephropathy in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).There were no differences between the observation and the control group in mesangial proliferative lesions,membranous proliferative nephritis,minimal lesions and membranous nephropathy(P>0.05).The incidences of diabetic nephropathy and hypertensive renal injury in the observation group were lower than those in the control group,and the incidence of purpura nephritis was lower than that in the control group,and the differences were statistically significant(P<0.05).There were no differences in the incidences of lupus nephritis and amyloidosis between the observation group and the control group(P>0.05).Conclusion The pathological diagnosis of renal biopsy in children with renal diseases had a high accuracy rate for the diagnosis of renal diseases,which was significantly different from that of adult renal diseases.It was conducive to the accurate diagnosis of classification,and the development of more effective disease intervention measures,which was worth

关 键 词：小儿 肾脏疾病 肾活检 病理诊断 

分 类 号：R334.1[医药卫生—人体生理学]