针刺臂穴后脑皮层功能连接变化的静息态功能磁共振研究  

Research on fMRI Changes in Functional Connections of Cerebral Cortex at Resting after Needling at Binao

作　　者：李晓燕[1,2] 赵创 郭思思[1,2] 陈春兰 梁薇[1,2] 杨艳 刘志丹[1,2] LI Xiaoyan;ZHAO Chuang;GUO Sisi;CHEN Chunlan;LIANG Wei;YANG Yan;LIU Zhidan(Baoshan Branch of Shuguang Hospital Affiliated to Shanghai University of TCM,Shanghai 201999,China;Baoshan Branch of Shanghai Municipality Hospital of Integrative Medicine)

机构地区：[1]上海中医药大学附属曙光医院宝山分院,上海201999 [2]上海市宝山区中西医结合医院

出　　处：《西部中医药》2022年第12期152-155,共4页Western Journal of Traditional Chinese Medicine

基　　金：上海市科学技术委员会科研计划项目(17401931600);上海市人才发展资金资助计划(2020086);上海市宝山卫生青年医学人才培养项目(bswsyq-2017-A02);上海市宝山区中西医结合医院院级重点专科培育项目(BSYYZDZK-2019-03,BSYYZDZK-2019-04)。

摘　　要：目的:运用功能磁共振成像(functional magnetic resonance imaging,fMRI)技术,比较针刺干预前后静息态相关脑皮层功能连接变化,探讨针刺臂臑穴对脑功能影响的机制。方法:选择健康志愿者30人,先后作为针刺假臂臑穴组和针刺臂臑穴组进行针刺干预下的功能磁共振扫描。Siemens Avantol3.0T磁共振成像仪进行fMRI扫描,Matalab平台DPABI软件进行rs-fMRI数据处理与分析,以中央后回、丘脑、扣带回、颞下回作为种子点,采用种子区方法分析种子点与全脑的功能链接。结果:在针刺健康受试者假臂臑穴和臂臑穴的配对T检验中,丘脑、扣带回、颞下回分别于全脑的功能链接,均表现出针刺臂臑穴针刺的显著性强于针刺假臂臑穴。结论:针刺臂臑穴能增强丘脑、扣带回、颞下回的功能连接。Objective:To compare the changes in functional connections of cerebral cortex at resting after needling at Binao(LI14)by applying fMRI technology,and to discuss the mechanism of the effects of needling Binao on cerebral function.Methods:All 30 healthy volunteers were chosen as the sham Binao group and acupuncture at Binao group,to conduct fMRI scan after acupuncture intervention.Siemens Avantol 3.0T MRI was used to perform fMRI scan,and Matalab platform DPABI software to process and analyze rs-fMRI data,with the posterior central gyrus,thalamus,cingulate gyrus and inferior temporal gyrus as seed points,the functional links between seed points and the whole brain were analyzed by the seed region method.Results:In the paired t-test of acupuncture at sham Binao and Binao in healthy subjects,the functional links of thalamus,cingulate gyrus and inferior temporal gyrus to the whole brain showed that acupuncture at brachial point was more significant than acupuncture at sham Binao.Conclusion:Needling at Binao could enhance the functional links of thalamus,cingulate gyrus and inferior temporal gyrus.

关 键 词：眼睑闭合不全 针刺 功能磁共振成像技术 臂臑穴 

分 类 号：R445.2[医药卫生—影像医学与核医学]