揿针疗法对肝癌患者肝动脉化疗栓塞术后血清胃泌素、胃动素及胃肠功能的影响  

Effect of Thumbtack Needling Therapy on Serum Gastrin and Motilin and Gastrointestinal Function of Liver Cancer Patients after TACE

作　　者：吴志敏 张珂畅 刘俊宏 张跃强 WU Zhi-min;ZHANG Ke-chang;LIU Jun-hong;ZHANG Yue-qiang(Department of Acupuncture and Moxibustion,Rehabilitation Center,Zhoukou Hospital of Traditional Chinese Medicine,Zhoukou Henan 466000)

机构地区：[1]河南省周口市中医院康复中心针灸科,河南周口466000

出　　处：《世界中西医结合杂志》2022年第10期1985-1988,共4页World Journal of Integrated Traditional and Western Medicine

基　　金：河南中医药科学研究专项课题(2016ZY3049)。

摘　　要：目的探讨揿针疗法对肝癌患者肝动脉化疗栓塞术(Transcatheter arterial chemoembolization,TACE)后血清胃泌素、胃动素及胃肠功能的影响。方法选取2018年1月—2021年1月期间周口市中医院收治的原发性肝癌患者90例,采用随机数字表法分为对照组和观察组,每组各45例。术后所有患者均给予基础处理措施,对照组予以枸橼酸莫沙必利片治疗,观察组在对照组基础上给予揿针疗法治疗。治疗7 d后,观察比较两组患者首次排气时间、首次排便时间、肠鸣音恢复时间及并发症发生率,治疗前后血清胃泌素、胃动素水平,乏力、恶心、腹胀、腹痛评分情况。结果术后观察组首次排气时间、首次排便时间及肠鸣音恢复时间明显短于对照组,差异有统计学意义(P<0.05)。术后第7天两组患者血清胃泌素、胃动素水平均高于术后第1天,差异有统计学意义(P<0.05);且观察组血清胃泌素、胃动素水平明显高于对照组,差异有统计学意义(P<0.05)。术后第7天两组患者乏力、恶心、腹胀、腹痛评分均低于术后第1天,差异有统计学意义(P<0.05);且观察组乏力、恶心、腹胀、腹痛评分均明显低于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率11.11%明显低于对照组31.11%,差异有统计学意义(P<0.05)。结论揿针疗法能明显改善肝癌TACE术后胃肠功能受损症状,调节胃肠激素分泌,促进胃肠功能恢复,降低TACE术后并发症发生率。Objective To investigate the effect of thumbtack needling therapy(TNT)on serum gastrin and motilin and gastrointestinal function of patients with liver cancer after transcatheter arterial chemoembolization(TACE).Methods A total of 90 cases with primary liver cancer who were treated in Zhoukou Hospital of Traditional Chinese Medicinefrom January 2018 to January 2021 were randomized into the control group(n=45)and observation group(n=45)with random number table.After surgery,all the patients received basic treatment measures.The control group was added with Mosapride Citrate Tablets,and the observation group was added with Mosapride Citrate Tablets and TNT.The intervention lasted 7 days for both groups.The time of first exhaust,time of first defecation,time of bowel sound recovery,and incidence of complications in the two groups were recorded,and the levels of serum gastrin and motilin and scores of fatigue,nausea,abdominal distension,and abdominal pain were compared between the two groups before and after treatment.Results The first exhaust,first defecation,and bowel sound recoveryin the observation group were earlier than those in the control group(P<0.05).On the 7 th day after surgery,the levels of serum gastrin and motilin in the two groups were higher than those on the 1 st day after surgery(P<0.05),and the levels in observation group were higher than those in control group(P<0.05).On the 7 th day after surgery,the scores of fatigue,nausea,abdominal distension,and abdominal pain in the two groups were lower than those on the 1 st day after surgery(P<0.05),and the scoresin observation group were lower than those in control group(P<0.05).The incidence of postoperative complications in the observation group was 11.11%,as compared with the 31.11%in the control group(P<0.05).Conclusion After TACE for liver cancer patients,TNT can significantly improve the impaired gastrointestinal functions,regulate the secretion of gastrointestinal hormones,promote the recovery of gastrointestinal function,and reduce the incidence

关 键 词：揿针疗法 肝癌 肝动脉化疗栓塞术 胃泌素 胃动素 胃肠功能 

分 类 号：R245[医药卫生—针灸推拿学] R735.7[医药卫生—中医临床基础]