老年2型糖尿病患者合并结肠腺瘤性息肉的高危因素分析  

Analysis of high-risk factors of colonic adenomatous polyps in elderly patients with type 2 diabetes

作　　者：余凤娇 陈倩文 YU Feng-jiao;CHEN Qian-wen(Shanghai Sixth People's Hospital Haikou Hospital&Haikou Orthopaedic and Diabetes Hospital,570300 Haikou Hainan,China)

机构地区：[1]上海市第六人民医院海口医院&海口市骨科与糖尿病医院,海南海口570300

出　　处：《临床消化病杂志》2022年第6期450-453,共4页Chinese Journal of Clinical Gastroenterology

基　　金：海南省医药卫生科研项目(No:20A200384)。

摘　　要：[目的]探讨老年2型糖尿病患者结肠腺瘤性息肉发病的高危因素。[方法]选择行结肠镜检查的老年2型糖尿病患者223例,根据是否伴结肠腺瘤性息肉分为腺瘤组(114例)与无腺瘤组(109例)。单因素和多因素Logistic回归分析影响老年2型糖尿病患者结肠腺瘤性息肉发病的高危因素。[结果]经单因素分析显示,腺瘤组与无腺瘤组性别、年龄、吸烟史、受教育年限、体质指数、高血压史、冠心病史、糖化血红蛋白、总胆固醇、三酰甘油、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇比较均差异无统计学意义(P>0.05);腺瘤组与无腺瘤组长期饮酒史、胆囊疾病、幽门螺杆菌感染和胰岛素的使用比较差异有统计学意义(P<0.05)。上述单因素分析差异具有统计学意义的纳入多因素Logistic回归分析显示,长期饮酒史、胆囊疾病、幽门螺杆菌感染及胰岛素的使用为老年2型糖尿病患者结肠腺瘤性息肉发病的高危因素。[结论]老年2型糖尿病患者结肠腺瘤性息肉发病受多因素影响,长期饮酒史、胆囊疾病、幽门螺杆菌感染及胰岛素的使用为其高危因素。[Objective]To investigate the high-risk factors of colon adenomatous polyps in elderly patients with type 2 diabetes.[Methods]The 223 elderly patients with type 2 diabetes who underwent colonoscopy were selected.According to whether they had colon adenomatous polyps or not, they were divided into 114 cases in the adenoma group and 109 cases in the adenoma-free group..Single factor and multivariate Logistic regression analysis of high-risk factors affecting the incidence of colonic adenomatous polyps in elderly patients with type 2 diabetes.[Results]Univariate analysis showed that gender, age, smoking history, years of education, body mass index, history of hypertension, history of coronary heart disease, HbA1 c, TC, TG, LDL-C and HDL-The difference in comparison was not statistically significant(P>0.05);the differences in long-term drinking history, gallbladder disease, Helicobacter pylori infection and insulin use between the adenoma group and the adenoma-free group were statistically significant(P<0.05).The statistically significant differences in the above-mentioned single factor analysis included multivariate Logistic regression analysis, which showed that long-term drinking history, gallbladder disease, Helicobacter pylori infection, and insulin use are high-risk factors for colonic adenomatous polyps in elderly patients with type 2 diabetes.[Conclusion]Elderly patients with type 2 diabetes have a higher incidence of colon adenomatous polyps, and the incidence of colon adenomatous polyps is affected by many factors, and long-term drinking history, gallbladder disease, Helicobacter pylori infection and insulin use are high risk factors.

关 键 词：2型糖尿病 结肠腺瘤性息肉 高危因素 

分 类 号：R587.1[医药卫生—内分泌]