难治性癫痫患儿大脑半球切除术后运动功能的多模态磁共振成像评估  

Multimodal magnetic resonance imaging for assessment of motor function after hemispherectomy in children with refractory epilepsy

作　　者：赵一霖 刘心怡 曾洪武[2] Zhao Yilin;Liu Xinyi;Zeng Hongwu(Department of Radiology,Shenzhen Children′s Hospital,China Medical University,Shenzhen 518038,China;Department of Radiology,Shenzhen Children′s Hospital,Shenzhen 518038,China;Department of Radiology,Shenzhen Children′s Hospital,Shantou University Medical College,Shenzhen 518038,China)

机构地区：[1]中国医科大学深圳市儿童医院放射科,深圳518038 [2]深圳市儿童医院放射科,深圳518038 [3]汕头大学医学院深圳市儿童医院放射科,深圳518038

出　　处：《中华实用儿科临床杂志》2022年第23期1836-1840,共5页Chinese Journal of Applied Clinical Pediatrics

基　　金：深圳市"医疗卫生三名工程"项目(SZSM202011005)。

摘　　要：大脑半球切除术(HS)是治疗弥漫性半球病变难治性癫痫的一组有效外科术式。术后癫痫发作控制良好,部分患儿双侧肢体运动功能得以改善甚至恢复,这一结果突显出大脑的强大可塑性,遭受广泛损伤后的大脑可再行功能重组和皮质结构重塑,尤其在年幼患儿中更为明显。多模态磁共振成像技术可联合分析脑的结构和功能及相关神经影像学特征,揭示运动功能改善的神经生理机制。现就HS术后患儿运动功能改变的多模态磁共振成像研究进展进行综述。Hemispherectomy(HS)is an effective surgical therapy to treat refractory epilepsy caused by diffuse hemispheric disorders.After HS surgery,the seizures are often well controlled in patients,and the bilateral limb motor function improves even recovers in some children.This result reveals the strong neuronal plasticity of the brain.The brain,especially of young children,can achieve functional reorganization and cortical remodeling after extensive damage.Multimodal magnetic resonance imaging techniques can jointly analyze the structure and function of the brain and associated neuroimaging features to reveal the neurophysiological mechanisms underlying improved motor function.In this paper,the progress of multimodal magnetic resonance imaging research on motor function alterations in children after hemispherectomy was reviewed.

关 键 词：大脑半球切除术 运动功能 磁共振成像 儿童 

分 类 号：R726.5[医药卫生—儿科]