单纯性肥胖男童阴茎睾丸发育不良监测及治疗分析  

Monitoring and treatment of penile and testicular dysplasia in simple obese boys

作　　者：瞿秋萍 童方运 唐芳[1] 胡建军 Qu Qiuping;Tong Fangyun;Tang Fang;Hu Jianjun(Physical Examination Center of Hunan Children′s Hospital,Changsha 410007,China;Department of Urology,Hunan Children′s Hospital,Changsha 410007,China)

机构地区：[1]湖南省儿童医院体检中心,长沙410007 [2]湖南省儿童医院泌尿外科,长沙410007

出　　处：《国际泌尿系统杂志》2023年第1期121-125,共5页International Journal of Urology and Nephrology

摘　　要：目的对单纯性肥胖男童的阴茎睾丸发育情况进行监测,探讨肥胖与阴茎睾丸发育不良的相关性及其治疗方法。方法收集2021年1月至2021年12月经本院儿童保健科门诊诊断为单纯性肥胖的215例患儿的临床资料(肥胖组),于泌尿外科门诊行性发育量表监测,监测指标包括患儿阴茎长度(静息状态及最大牵拉状态)、睾丸大小(长径及宽径)、性轴全套水平[卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)、麝香草酚浊度试验(TTT)],以同年龄段207例正常体重男童测量值为对照组,比较肥胖组与对照组之间的差异。并对肥胖组男童采用人绒毛膜促性腺激素(HCG)注射及儿童短小阴茎治疗仪治疗,比较治疗前后的阴茎睾丸变化情况。结果肥胖组患儿的阴茎长度、睾丸大小均低于对照组,差异均有统计学意义(均P<0.05)。肥胖组男童的FSH、LH、TTT水平较对照组偏低,E2较对照组偏高,差异均有统计学意义(均P<0.001)。肥胖男童治疗后的阴茎长度及睾丸大小较治疗前均有所增长,差异有统计学意义(均P<0.05)。单纯性肥胖男童HCG注射治疗后的FSH、LH、TTT水平较治疗前升高,差异均有统计学意义(均P<0.05),但治疗前后的E2比较,差异无统计学意义(P>0.05)。结论肥胖对男童的阴茎睾丸发育存在一定影响,临床监测提示有阴茎睾丸发育不良的现象,需尽早控制体重,提前干预并予以科学治疗有利于性腺的发育。Objective To monitor the development of penis and testis in simple obese boys,and to explore the correlation between obesity and penile and testicular dysplasia and its treatment.Methods The data of 215 children diagnosed as simple obesity in the outpatient department of children's health care of our hospital from January 2021 to December 2021 were collected.The sexual development scale was monitored in the urology outpatient department.The monitoring indicators included penis length(rest,maximum traction),testicular size(length and width),and the complete level of sexual axis(FSH,LH,E2,TTT),207 normal weight boys of the same age group were used as the control group to compare the differences between the obese group and the control group.The obese boys were treated with HCG injection and children's short penis therapeutic instrument.The changes of penis and testis before and after treatment were compared.Results There were significant differences in penis length and testicular size between obese group and control group(all P<0.05).The effect of obesity on the level of sex hormone in boys was that FSH,LH and TTT were lower than those of control group,and E2 was higher than those of control group(all P<0.05).There was significant difference in the measured values of penis and testis between obese boys after treatment and before treatment(all P<0.05).FSH、LH、TTT of obese boys before and after HCG injection was significantly higher than that before HCG injection(all P<0.05).There was no significant difference in E2 before and after treatment(P>0.05).Conclusions Obesity has a certain impact on the penis and testis development of boys.Clinical monitoring suggests that there is a phenomenon of penis and testis dysplasia.It is necessary to control weight as soon as possible,intervene in advance and give scientific treatment,which is conducive to the development of gonads.

关 键 词：阴茎 睾丸 发育不良 儿童肥胖 

分 类 号：R726.9[医药卫生—儿科] R723.14[医药卫生—临床医学]