个体心理干预对艾滋病病毒感染者抗病毒治疗的影响  

Effect of individual psychological intervention on antiretroviral therapy in people living with HIV

作　　者：霍俊丽[1] 安晓静 韩瑜[1] 罗红兵[1] 牛瑾[1] 张小波[1] 杨志敏[1] 徐诺雅[1] 施玉华[1] 马艳玲 HUO Jun-li;AN Xiao-jing;HAN Yu;LUO Hong-bing;NIU Jin;ZHANG Xiao-bo;YANG Zhi-min;XU Nuo-ya;SHI Yu-hua;MA Yan-ling(Yunnan Center for Disease Control and Prevention,Kunming,Yunan 650022,China;不详)

机构地区：[1]云南省疾病预防控制中心,云南昆明650022 [2]云南省艾滋病研究所,云南昆明650022

出　　处：《现代预防医学》2023年第2期360-364,共5页Modern Preventive Medicine

基　　金：“十三五”科技重大专项“云南省防治艾滋病规模化现场流行病学和干预研究”项目(2018ZX10715006)。

摘　　要：目的通过对艾滋病病毒感染者开展心理干预,了解心理健康水平中介因素对抗病毒治疗接受性和服药依从性的影响。方法以认知疗法和支持性心理疗法为理论基础,由省级心理学专业团队设计了个体心理干预方案,结合日常随访工作,培训合格的随访医生实施个体干预。通过对600例艾滋病病毒感染者的干预对照研究,比较干预前后感染者各项指标变化情况。结果干预后,干预组的抗病毒治疗比例(χ^(2)=16.546,P<0.001)和在治依从性良好比例(χ^(2)=12.693,P<0.001)均显著高于对照组;与对照组相比,干预组的艾滋病压力评分(t=-38.507,P<0.001)、焦虑评分(t=-36.907,P<0.001)、抑郁评分(t=-36.567,P<0.001)、消极应对评分(t=-12.497,P<0.001)显著下降;社会支持评分(t=33.172,P<0.001)、积极应对评分(t=8.332,P<0.001)显著上升。结论个体心理干预可有效提高艾滋病病毒感染者心理健康水平,心理健康水平的提高对抗病毒治疗的接受性和服药依从性有促进作用。Objective To understand the influence of the intermediary factors of mental health level on the acceptance of antiviral treatment and drug compliance through psychological intervention for people living with HIV. Methods On the theoretical basis of cognitive therapy and supportive psychotherapy, an individual psychological intervention program was designed by the provincial psychology professional team, combined with daily follow-up. Qualified follow-up doctors were trained to carry out individual intervention. Through the intervention control study of 600 cases of HIV infection, the changes of various indexes of HIV infection before and after intervention were compared. Results After intervention, the proportion of receiving antiretroviral therapy(χ^(2)=16.546, P<0.001) and the proportion of compliance with antiretroviral therapy(χ^(2)=12.693,P<0.001) in the intervention group significantly increased compared with the control group. The HIV stress score( t=-38.507,P<0.001), anxiety score(t=-36.907, P<0.001), depression score(t=-36.567, P<0.001), and negative coping score(t=-12.497,P<0.001) of the intervention group were significantly lower than that of the control group. The social support score( t=33.172,P<0.001) and positive coping score(t=8.332, P<0.001) of the intervention group were significantly higher than that of the control group. Conclusion Individual psychological intervention can effectively improve the mental health level of HIV infected people, and the improvement of mental health level can promote the acceptance of antiviral treatment and drug compliance.

关 键 词：个体心理干预 抗病毒治疗 艾滋病病毒感染者 

分 类 号：R512.91[医药卫生—内科学]