经术侧肢体采血对乳腺癌根治术后病人淋巴水肿的影响  

Effect of blood collection from operative limb on lymphedema in patients with breast cancer after radical mastectomy

作　　者：杜春霖 徐梦露 谭明英[1] DU Chunlin;XU Menglu;TAN Mingying(West China Hospital,Sichuan University,Sichuan 610041 China)

机构地区：[1]四川大学华西医院,四川610041

出　　处：《护理研究》2023年第2期212-215,共4页Chinese Nursing Research

基　　金：四川省科技计划项目,编号:2019YFS0385。

摘　　要：目的:探索经术侧肢体采血对乳腺癌根治术后病人淋巴水肿的影响。方法:于2019年7月—2020年12月选取我院220例乳腺癌根治术后病人作为研究对象,采用随机数字表法将病人分为试验组和对照组,每组110例。对照组选用健侧肢体采血,试验组选用术侧肢体采血。测量病人采血前、采血后1 d、采血后7 d、采血后28 d的术侧肢体、健侧肢体臂围,采用广义估计方程比较试验组和对照组间、各时点间的臂围差异。结果:剔除失访、死亡病人,最终纳入的病人共190例,其中,试验组81例,对照组109例,除血管情况外,两组一般资料比较,差异均无统计学意义(P>0.05)。广义估计方程结果显示,试验组和对照组的术侧肢体、健侧肢体臂围差异无统计学意义(P>0.05),在各测量时点差异无统计学意义(P>0.05);血管情况作为协变量,其偏回归系数无统计学意义(P>0.05)。结论:经术侧肢体采血对于乳腺癌根治术后病人淋巴水肿影响不明显。Objective:To explore effect of blood collection from operative limb on lymphedema in patients with breast cancer after radical mastectomy.Methods:A total of 220 patients with breast cancer after radical mastectomy in our hospital were selected as research subjects from July 2019 to December 2020.The patients were randomly divided into test group and control group,with 110 cases in each group.The healthy limb was selected for blood collection in control group,and operative limb was selected for blood collection in test group.Measure arm circumference of operative limb and healthy limb of patient before blood collection,at 1 day after blood collection,at 7 days after blood collection,and at 28 days after blood collection.Arm circumference difference between test group and control group,and arm circumference difference among different time points were compared by generalized estimating equation.Results:A total of 190 patients were finally included after excluding lost and dead patients,including 81 patients in test group and 109 patients in control group.Except for vascular conditions,there was no significant difference between two groups in terms of general information(P>0.05).The results of the generalized estimation equation showed that there was no statistically significant difference between test group and control group in arm circumference of operative side and healthy side(P>0.05),and there was no statistically significant difference among each measurement time point in arm circumference of operative side and healthy side(P>0.05).As covariate,partial regression coefficient of blood vessel was not statistically significant(P>0.05).Conclusions:Blood collection from operative limb has no significant effect on lymphedema in patients with breast cancer after radical mastectomy.

关 键 词：乳腺癌 采血 淋巴水肿 臂围 广义估计方程 护理 

分 类 号：R473.73[医药卫生—护理学]