近4年本院感染性病原菌的分布及耐药监测情况分析  

Analysis of the Distribution and Drug Resistance Monitoring of Infectious Pathogens in the Hospital in the Past 4 Years

作　　者：陈阿红[1] 许英[1] CHEN Ahong;XU Ying(Department of Laboratory,Taizhou City Hospital of Traditional Chinese Medicine,Taizhou,Jiangsu Province,225300 China)

机构地区：[1]泰州市中医院检验科,江苏泰州225300

出　　处：《系统医学》2022年第20期58-61,65,共5页Systems Medicine

摘　　要：目的了解泰州市中医院重点科室重症监护病房(intensive care unit,ICU)、血液科、呼吸科、老年科病原菌的分布特点及细菌药敏情况,为院内病原菌的控制及指导临床如何合理用药提供参考价值。方法回顾性分析泰州市中医院近4年检测出来的病原菌分布以及耐药情况。结果革兰阴性杆菌(gram-negative rod,GNR)855/1317占比64.9%,革兰阳性球菌(gram-positive bacterium,GPB)288/1317占比21.9%,真菌174/1317占比13.2%。耐药统计鲍曼不动杆菌的耐药率达到89.1%,肺炎克雷伯菌对常见第三代、四代头孢菌素类药物的耐药率达55.0%;耐碳青霉烯类肺炎克雷伯菌、耐万古的肠球菌4年来检出率的变化不明显,分别为由31.1%下降至23.6%、由2.56%下降至6.25%,耐碳青霉烯类铜绿假单胞菌、鲍曼不动杆菌,耐甲氧西林金黄色葡萄球菌检出率呈下降趋势,分别为由77.5%下降至29.4%、由83.0%下降至61.1%、由61.1%下降至24.0%。结论需定期对重点科室的细菌分布及细菌药敏监测进行分析总结,及时与临床取得沟通,控制抗菌药物的使用。Objective To understand the distribution characteristics and bacterial drug sensitivity of pathogenic bacteria in intensive care unit(ICU),hematology department,respiratory department and geriatric department of Taizhou City Hospital of Traditional Chinese Medicine,so as to provide reference value for the control of pathogenic bacteria in the hospital and guide how to use drugs rationally in the clinic.Methods The distribution and drug resistance of pathogenic bacteria detected in Taizhou City Hospital of Traditional Chinese Medicine in recent 4 years were analyzed retrospectively.Results Gram-negative rod(GNR)855/1317 accounted for 64.9%,gram-positive bacterium(GPB)288/1317 accounted for 21.9%,and fungi 174/1317 accounted for 13.2%.Drug resistance statistics showed that the resistance rate of Acinetobacter baumannii reached 89.1%,and the resistance rate of Klebsiella pneumoniae to common third and fourth generation cephalosporins reached 55.0%.The detection rates of carbapenem resistant pneumococci and vancomycin resistant enterococci did not change significantly in the past four years,which were from 31.1%to 23.6%and from 2.56%to 6.25%,respectively.The detection rates of carbapenem-resistant Pseudomonas aeruginosa and Bowman were not moved,and methicillin-resistant Staphylococcus aureus showed a decreasing trend,which were from 77.5%to 29.4%,from 83.0%to 61.1%,and from 61.1%to 24.0%,respectively.Conclusion Bacterial distribution and bacterial drug sensitivity monitoring in key departments should be analyzed and summarized regularly,and timely communication with clinical departments is needed to control the use of antibacterial drugs.

关 键 词：重点科室 病原菌 耐药性 多重耐药菌 细菌药敏检测 

分 类 号：R446[医药卫生—诊断学]