结核性气管支气管狭窄球囊扩张并发症影响因素分析  

Analysis of the factors affecting complications of balloon dilation in tuberculous tracheobronchial stenosis

作　　者：郑婷 周霞 陈慧冬 张梦 ZHENG Ting;ZHOU Xia;CHEN Hui-dong;ZHANG Meng(Wuhan Jinyintan Hospital,Tongji Medical College of Huazhong University of Science and Technology,Hubei Clinical Research Center for Infectious Diseases,Wuhan Research Center for Communicable Disease Diagnosis and Treatment,Chinese Academy of Medical Sciences,Joint Laboratory of Infectious Diseases and Health,Wuhan Institute of Virology and Wuhan Jinyintan Hospital,Chinese Academy of Sciences,Wuhan 430023,China)

机构地区：[1]华中科技大学同济医学院附属武汉金银潭医院(呼吸内镜介入科)、湖北省传染病临床医学研究中心、中国医学科学院武汉传染性疾病诊治研究中心、中国科学院武汉病毒研究所&武汉市金银潭医院感染性疾病与健康联合实验室,湖北武汉430023

出　　处：《临床肺科杂志》2023年第2期163-166,共4页Journal of Clinical Pulmonary Medicine

基　　金：武汉市卫生和计划生育委员会科研项目(No.WX15B21)。

摘　　要：目的研究结核性气管支气管狭窄经球囊扩张后出现并发症的影响因素。方法回顾2017年4月1日-2022年4月1日在武汉市金银潭医院接受支气管镜下球囊扩张术用以改善气道狭窄的气管支气管结核患者,所有患者均经敏感方案抗结核治疗并于全麻下行球囊扩张术,按是否发生并发症分为两组,统计分析两组的临床资料。结果共214例患者,其中男性56例,女性158例,年龄15~74岁,出现并发症者35例(16.4%),其中27例(12.6%)出现无法自行缓解的出血,5例(2.3%)出现管壁透壁撕裂,3例(1.4%)扩张后出现管壁软化。单因素Logistic回归分析提示狭窄长度(P<0.01,OR=2.023)、狭窄类型(P<0.01,OR=3.733)差异有显著统计学意义;多因素Logistic回归显示狭窄长度(P<0.01,OR=1.815)差异有显著统计学意义,狭窄类型(P<0.05,OR=2.668)差异有统计学意义。结论狭窄长度较长及瘢痕挛缩型结核性气管支气管狭窄患者更易在接受球囊扩张后出现并发症。Objective To analyze the factors leading to complications of tuberculous tracheobronchial stenosis after balloon dilatation.Methods The clinical data of the patients with tracheobronchial tuberculosis who underwent bronchoscopic balloon dilation to improve airway stenosis from April 1,2017 to April 1,2022 at Wuhan Jinyintan Hospital were retrospectively analyzed.All patients received anti-tuberculosis medication and underwent balloon dilation under general anesthesia.They were divided into two groups according to whether complications occurred,and the clinical data of the two groups were statistically analyzed.Results There were a total of 214 patients,including 56 males and 158 females,aged 15~74 years old.Complications occurred in 35 cases(16.4%),including 27 cases(12.6%)with unremitting bleeding,5 cases(2.3%)with permeable tracheal laceration,and 3 cases(1.4%)with tracheal softening after dilation.Single-factor logistic regression analysis suggested that there were statistically significant differences in stenosis length(P<0.01,OR=2.023)and stenosis type(P<0.01,OR=3.733).Multi-factor logistic regression showed that there were statistically significant differences in stenosis length(P<0.01,OR=1.815)and stenosis type(P<0.05,OR=2.668)were statistically significant.Conclusion Patients with longer stenosis length and scar contracture type tuberculous tracheobronchial stenosis are more likely to develop complications after receiving balloon dilation treatment.

关 键 词：支气管镜 球囊扩张 气管支气管结核 并发症 

分 类 号：R523[医药卫生—内科学]