临床药师参与心脏瓣膜置换术后抗凝不足致疑似急性冠脉栓塞抗栓治疗一例  

Pharmaceutical care of antithrombotic treatment for suspected acute coronary embolism caused by inadequate anticoagulation after cardiac valve replacement:a case report

作　　者：郭丽萍[1] 李雪 袁冬冬[1] GUO Li-ping;LI Xue;YUAN Dong-dong(Department of Pharmacy,the Seventh People's Hospital of Zhengzhou,Henan Zhengzhou 450016,China)

机构地区：[1]郑州市第七人民医院药学部,河南郑州450016

出　　处：《临床药物治疗杂志》2022年第12期87-89,共3页Clinical Medication Journal

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20210749)。

摘　　要：本文报告1例临床药师参与的心脏机械瓣置换术后继发疑似急性冠脉栓塞事件的抗栓治疗。临床药师结合病例特点并查阅文献、指南,分析达比加群酯抗凝不足为冠脉栓塞事件诱因,协助医师制定华法林、阿司匹林和氯吡格雷三联抗栓方案,借助基因检测等技术优化抗栓药物疗效,分析抗栓药物致消化道出血风险并适时降低抗栓强度,保障患者用药安全有效。Inadequate anticoagulation after cardiac valve replacement significantly increases the risk of thromboembolic events.This paper reported the process of antithrombotic therapy for a patient with suspected acute coronary embolism after mechanical cardiac valve replacement.Clinical pharmacists identified that inadequate anticoagulation was the cause of coronary embolism,and assisted physicians to develop the triple antithrombotic treatment,optimized the efficacy of antithrombotic drugs by gene testing,analyzed the risk of gastrointestinal injury caused by antithrombotic drugs and timely reduce the antithrombotic strength,so as to ensure the safety and effectiveness of medication for patients.

关 键 词：心脏瓣膜置换术 冠状动脉栓塞 抗栓治疗 消化道出血 

分 类 号：R969.3[医药卫生—药理学]