急性ST段抬高型心肌梗死患者应用血栓抽吸导管的临床效果及对心功能和心率变异性的影响  

The Clinical Effect of Thrombus Aspiration Catheter in Patients with Acute ST-segment Elevation Myocardial Infarction and its Effect on Cardiac Function and Heart Rate Variability

作　　者：刘革铭 马洪俊 刘毅 王玉平 LIU Ge-ming;MA Hong-jun;LIU Yi;WANG Yu-ping(Department of Cardiology,Binhai New Area Haibin People's Hospital,Tianjin 300280,China)

机构地区：[1]天津市滨海新区海滨人民医院心血管内科,天津300280

出　　处：《医学信息》2022年第24期127-129,共3页Journal of Medical Information

摘　　要：目的探讨急性ST段抬高型心肌梗死患者应用血栓抽吸导管的临床效果及对心功能和心率变异性的影响。方法选取2020年1月-2021年7月我院收治的急性ST段抬高型心肌梗死患者中行PCI术且成功应用血栓抽吸导管的患者72例为试验组,另选取同期收治的行PCI术患者65例为对照组。比较两组临床效果(心脏损伤标志物、心电图ST段回落变化)、心功能指标[左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、左室射血分数(LVEF)]、心率变异性指标[窦性心搏RR间期标准差(SDNN)、R间期平均值标准差(SDANN)、相邻RR间期差值均方根(RMSSD)]。结果试验组cTnⅠ、CK-MB水平低于对照组,ST段回落率高于对照组,差异有统计学意义(P<0.05);试验组LVEDD、LVESD水平低于对照组,LVEF水平高于对照组,差异有统计学意义(P<0.05);试验组SDNN、SDANN、RMSSD高于对照组,差异有统计学意义(P<0.05)。结论急性ST段抬高型心肌梗死患者在行PCI治疗基础上应用血栓抽吸导管治疗可降低患者的心肌受损情况,在改善患者的心功能、心率变异性及心电图ST完全回落率方面效果明显,具有较高的临床应用价值。Objective To investigate the clinical effect of thrombus aspiration catheter in patients with acute ST-segment elevation myocardial infarction and its effect on cardiac function and heart rate variability.Methods A total of 72 patients with acute ST-segment elevation myocardial infarction who underwent PCI and successfully applied thrombus aspiration catheter in our hospital from January 2020 to July 2021 were selected as the experimental group,and 65 patients who underwent PCI during the same period were selected as the control group.The clinical effect(cardiac injury markers,electrocardiogram ST segment resolution),cardiac function indexes[left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular ejection fraction(LVEF)],heart rate variability indexes[standard diviation of NN intervals(SDNN),standard diviation average of NN intervals(SDANN),root mean square difference of adjacent RR interval(RMSSD)]were compared between the two groups.Results The levels of c TnI and CK-MB in the experimental group were lower than those in the control group,and the ST segment resolution rate was higher than that in the control group,the differences were statistically significant(P<0.05).The levels of LVEDD and LVESD in the experimental group were lower than those in the control group,and the level of LVEF was higher than that in the control group,the differences were statistically significant(P<0.05).SDNN,SDANN and RMSSD in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The application of thrombus aspiration catheter in patients with acute ST-segment elevation myocardial infarction on the basis of PCI treatment can reduce the myocardial damage of patients,and has obvious effect in improving the cardiac function,heart rate variability and complete ST drop rate of electrocardiogram,which has high clinical application value.

关 键 词：急性ST段抬高型心肌梗死 血栓抽吸 心功能 心率变异性 

分 类 号：R542.22[医药卫生—心血管疾病]