基于“毒、瘀”病机对桃红四物汤防治肢体缺血-再灌注损伤理论探讨  

Approach to Taohong Siwu decoction for prevention and treatment of limb ischemia-reperfusion injury based on the pathogenesis of toxin and blood-stasis

作　　者：陈科祥 朱付平 顾启帆 李慎富 CHEN Ke-xiang;ZHU Fu-ping;GU Qi-fan(Hunan University of Traditional Chinese Medicine,Changsha 410208,China;不详)

机构地区：[1]湖南中医药大学,长沙410208 [2]湖南中医药大学第一附属医院

出　　处：《山西中医》2023年第1期1-3,共3页Shanxi Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:81674008);湖南省自然科学基金项目(编号:2020JJ4070);湖南省卫生健康委重点课题项目(编号:202204072465)。

摘　　要：以“毒、瘀”病机为角度,探讨“毒、瘀”病机与肢体缺血-再灌注损伤复杂的发病机制的关联性及桃红四物汤对肢体缺血-再灌注损伤的重要防护作用,认为“毒、瘀”是引起肢体缺血-再灌注损伤的重要发病因素;桃红四物汤通过化瘀生新,活血减毒在防治肢体缺血-再灌注损伤中发挥保护作用;为肢体缺血-再灌注损伤的中医辨证论治提供新思路。Based on the theory of toxin and blood-stasis,to approach to the correlativity between pathogenesis of toxin and blood-stasis and complex nosogenesis of limb ischemia-reperfusion injury and the important protective effect of Taohong Siwu decoction on limb ischemia-reperfusion injury.It is believed that toxin and blood-stasis are important pathogenic factors caused limb ischemia-reperfusion injury.Taohong Siwu decoction has the protective effect on prevention and treatment of limb ischemia-reperfusion injury by removing blood-stasis for promoting blood regeneration and promoting blood circulation for detoxication,which provide a new idea for TCM syndrome differentiation and treatment of limb ischemia-reperfusion injury.

关 键 词：肢体缺血-再灌注损伤 毒 瘀 病机 桃红四物汤 

分 类 号：R259[医药卫生—中西医结合]