有氧和抗阻运动对糖尿病前期人群腹部脂肪和代谢指标的影响  

Effect of a12-month resistance training and aerobic training in abdominal adipose tissue and metabolic variables in patients with pre-diabetes:a randomized controlled trial

作　　者：周倩倩 楼青青[2] 严娟 冯纪涛[4] 姚金兰[1] 刘晓蓉[5] ZHOU Qianqian;LOU Qingqing;YAN Juan;FENG Jitao;YAO Jinlan;LIU Xiaorong(School of Medical and Nursing Huzhou University,Huzhou,Zhejiang,313000;Department of Health Education,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210028;Jiangsu College of Nursing,Huaian,Jiangsu,213001;Department of Radiology,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210028;Department of Nursing,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210028)

机构地区：[1]湖州师范学院医学院护理学院,浙江湖州313000 [2]南京中医药大学附属中西医结合医院,江苏省中医药研究院,江苏省中西医结合医院健康教育科,江苏南京210028 [3]江苏护理职业学院,江苏淮安213001 [4]南京中医药大学附属中西医结合医院,江苏省中医药研究院,江苏省中西医结合医院放射科,江苏南京210028 [5]南京中医药大学附属中西医结合医院,江苏省中医药研究院,江苏省中西医结合医院护理部,江苏南京210028

出　　处：《中西医结合护理》2021年第1期29-35,共7页Chinese Journal of Integrative Nursing

基　　金：国家自然科学基金面上项目(81370923);国家中医药管理局科研基金(JDZX2015132)。

摘　　要：目的探讨抗阻运动与有氧运动对成人糖尿病前期人群腹部脂肪和代谢指标的影响。方法选取2014年5月—2015年4月期间在江苏省中西医结合医院及丹阳市人民医院就诊的糖尿病前期患者105例,随机分为有氧运动组(AT,n=35),抗阻运动组(RT,n=35)和对照组(n=35)。AT组进行12个月的有氧运动干预,RT组进行12个月的抗阻运动干预,对照组常规干预。观察入组时和干预12个月后人体成分和代谢指标,使用计算机断层扫描(CT)测量腹部和内脏脂肪(VAT)和皮下脂肪(SAT)。结果干预后AT组和RT组VAT较对照组显著降低(P=0.001,P=0.014)。AT组和RT组SAT显著下降(P<0.05)。RT组肌肉量增加高于AT组和对照组(P=0.031,P=0.045)。与对照组比较,AT组和RT组空腹血糖(FPG)明显降低(P=0.014,P=0.003)。结论抗阻运动和有氧运动均能有效减少糖尿病前期人群的VAT和FPG水平,抗阻运动增加肌肉量的效果更加显著。Objective To investigate the effects of resistance exercise and aerobic exercise on abdominal adipose tissue and metabolic indexes in adults with pre-diabetes.Methods From May 2014 to April 2015,105 patients with pre-diabetes were randomly divided into aerobic exer⁃cise group(AT,n=35),resistance exercise group(RT,n=35)and control group(n=35).Pa⁃tients in the intervention group completed aerobic exercise and resistance exercise for 12 months,control group maintained the original lifestyle without exercise intervention.Relevant indicators were measured at the time of enrollment and 12 months of intervention.The main outcome indica⁃tors were visceral adipose tissue(VAT)and subcutaneous adipose tissue(SAT)measured by computed tomography(CT).The secondary outcome indicators were body composition,lipid distribution and metabolic variables.Results A total of 93 participants completed the study.There was no significant difference between the groups before intervention(P>0.05).After inter⁃vention,the VAT of AT and RT was significantly lower than that of control group(P=0.001,P=0.014,respectively).Although there was no significant difference in SAT between different groups,the SAT in each exercise group decreased significantly over time(P=0.001).The in⁃crease of muscle mass in RT was higher than that in AT and control group(P=0.031,P=0.045,respectively).Compared with control group,fasting plasma glucose(FPG)of AT and RT was significantly decreased(P=0.014,P=0.003,respectively).Conclusion Both aerobic exercise and resistance exercise can significantly reduce the abdominal fat content and FPG among patients with pre-diabetes.In addition,the effect of resistance exercise on increasing muscle mass is more remarkable.

关 键 词：有氧运动 抗阻运动 腹部脂肪 代谢指标 糖尿病前期患者 

分 类 号：R473.5[医药卫生—护理学]