针灸改善认知功能障碍机制的研究进展  

Research progress of mechanisms of acupuncture and moxibustion on improving cognitive dysfunction

作　　者：杨新月 王之虹[1] YANG Xinyue;WANG Zhihong(Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]长春中医药大学,长春130117

出　　处：《吉林中医药》2023年第1期120-123,共4页Jilin Journal of Chinese Medicine

基　　金：中国工程院院地合作项目(JL2020-005);长春中医药大学研究生“橘井杯”学术科研创新及创业项目(YK202111)。

摘　　要：针灸治疗认知功能障碍临床疗效确切,但机制尚不明确,研究发现,针灸改善认知功能障碍的作用机制可能是通过调节全身炎症反应并且减缓神经炎症的发展,调节氧化应激,改善突触的可塑性,减少神经元损伤并提供神经保护,调整海马中葡萄糖代谢等实现。通过对作用机制现状研究,以期为针灸治疗认知功能障碍提供理论基础与依据。Acupuncture and moxibustion has a definite clinical effect on cognitive dysfunction,but its mechanisms are not clear yet.Studies have found that acupuncture and moxibustion improves the cognitive dysfunction possibly through regulating the systemic inflammation response and slowing down the development of neuroinflammation,regulating the oxidative stress response,improving the synaptic plasticity,reducing the neuronal impairment and providing neuroprotection,and adjusting the glucose metabolism in the hippocampus.By studying the current situation of the mechanisms of acupuncture and moxibustion,it is expected to provide a theoretical basis for the treatment of cognitive dysfunction with acupuncture and moxibustion.

关 键 词：针灸 认知功能障碍 机制 炎症调节 氧化应激 突出可塑性 保护神经元 海马葡萄糖代谢 

分 类 号：R246.6[医药卫生—针灸推拿学]