中性粒细胞在COVID-19发生发展中作用的研究进展  

Role of neutrophils in the development and progression of COVID-19

作　　者：王亮 司萍[1] 沈永明[1] 崔晓鸣[1] WANG Liang;SI Ping;SHEN Yongming;CUI Xiaoming(Department of Clinical Laboratory,Tianjin Children's Hospital/Children's Hospital of Tianjin University,Tianjin 300074,China)

机构地区：[1]天津市儿童医院/天津大学儿童医院检验科,天津300074

出　　处：《基础医学与临床》2023年第2期341-345,共5页Basic and Clinical Medicine

摘　　要：中性粒细胞是COVID-19感染中出现较多的固有免疫细胞。中性粒细胞数量以及血浆中性粒细胞胞外诱捕网(NETs)水平与COVID-19严重程度呈正相关。本文综述中性粒细胞以及NETs的生成与降解参与COVID-19的病理过程,以期对深入研究COVID-19的发病机制以及疾病干预提供借鉴。Neutrophils are more innate immune cells found in coronavirus disease in 2019(COVID-19).The accounting of neutrophils and the level of plasma neutrophil extracellular traps(NETs)were positively correlated with the severity of COVID-19.This article reviews the relevant studies of neutrophils,formation and degradation of NETs involved in the pathological process of COVID-19,providing the reference for further studies of pathogenesis and intervention.

关 键 词：COVID-19 SARS-CoV-2 中性粒细胞 中性粒细胞胞外诱捕网 

分 类 号：R512.99[医药卫生—内科学]