广西壮族人群糖代谢异常流行病学特征及其主要影响因素分析  

Epidemiological characteristics and main influencing factors of abnormal glucose metabolism in Guangxi Zhuang population

作　　者：梁金良 姚贤聪 农秋峰 秦萃 黄春雀 钟嘉欣 杜佳恒 潘智敏 李太生 李海 LIANG Jin-liang;YAO Xian-cong;NONG Qiu-feng;QIN Cui;HUANG Chun-que;ZHONG Jia-xin;DU Jia-heng;PAN Zhi-min;LI Tai-sheng;LI Hai(Department of Epidemiology,School of Public Health and Management,Guangxi University of Traditional Chinese Medicine,Nanning,Guangxi 530200,China)

机构地区：[1]广西中医药大学公共卫生与管理学院流行病学教研室,广西南宁530200 [2]南宁市南湖竹溪社区卫生服务中心 [3]隆安县疾病预防控制中心

出　　处：《应用预防医学》2022年第6期501-505,509,共6页Applied Preventive Medicine

基　　金：大学生创新创业训练计划项目(S202110600128)。

摘　　要：目的了解广西地区壮族人群糖代谢异常的流行特征及主要危险因素,为制定防控措施提供参考依据。方法采用非匹配病例对照研究方法,选取在医疗机构进行诊治的糖代谢异常者100例为病例组,另选取非糖代谢异常其他就诊者或健康人200例为对照组。对调查对象进行问卷调查,问卷内容包括一般资料、生活习惯、饮食结构、民俗习惯、精神压力、心理因素、疾病史等。采用χ^(2)检验或秩和检验比较两组的基本特征与基础病史情况;采用logistic回归模型进行单因素和多因素分析。结果300例调查对象的平均年龄为(49.96±14.39)岁,男性占43.7%,男、女比例为1∶1.29。多因素非条件logistic回归模型分析显示,女性[OR=0.361(95%CI:0.194-0.671),P=0.001]、教育程度高[OR=0.497(95%CI:0.321-0.770),P=0.002]是糖代谢异常的保护因素,不确定是否向他人倾诉烦恼[OR=4.013(95%CI:1.966-8.194),P<0.001]、不会向他人倾诉烦恼[OR=2.601(95%CI:1.251-5.405),P=0.010]、年龄增大[OR=1.808(95%CI:1.335-2.412),P<0.001]、有糖尿病家族史[OR=12.411(95%CI:4.996-30.831),P<0.001]、易暴躁激动[OR=1.940(95%CI:1.288-2.922),P=0.002]是糖代谢异常的危险因素。结论广西地区壮族居民糖代谢异常与多种因素有关,应针对影响因素对糖代谢异常人群进行干预,改善其血糖水平及相关临床症状。Objective To explore the epidemiological characteristics and main risk factors of abnormal glucose metabolism among Zhuang population in Guangxi area,and to provide a reference basis for formulating preventive and control measures.Methods Using a non-matching case-control study design,100patients with glucose metabolism abnormalities who were diagnosed and treated in medical institutions were selected as the case group,and 200 patients without abnormal glucose metabolism or healthy people were selected as the control group.A questionnaire survey including general information,living habits,dietary structure,folk customs,mental stress,psychological factors,disease history,and others was carried out.Theχ^(2) test or the rank sum test were used to compare the basic characteristics and basic medical history of the two groups,and the logistic regression model was used for univariate and multivariate analysis.Results The average age of the 300 participants was(49.96±14.39)years old,43.7%were male,and the ratio of male to female was 1∶1.29.Multivariate unconditional logistic regression analysis showed that female[OR=0.361(95%CI:0.194-0.671),P=0.001]and high education level[OR=0.497(95%CI:0.321-0.770),P=0.002]were protective factors for abnormal glucose metabolism.Uncertainty in confiding one’s troubles to the others[OR=4.013(95%CI:1.966-8.194),P<0.001],not telling others about troubles[OR=2.601(95%CI:1.251-5.405),P=0.010],increased age[OR=1.808(95%CI:1.335-2.412),P<0.001],family history of diabetes[OR=12.411(95%CI:4.996-30.831),P<0.001],irritability and agitation[OR=1.940(95%CI:1.288-2.922),P=0.002]were risk factors for abnormal glucose metabolism.Conclusions The abnormal glucose metabolism of Zhuang residents in Guangxi is related to a variety of factors.People with abnormal glucose metabolism should be intervened according to the influencing factors to improve their blood glucose level and related clinical symptoms.

关 键 词：糖代谢异常 病例对照研究 影响因素 

分 类 号：R589[医药卫生—内分泌]