沙眼衣原体致婴幼儿下呼吸道感染的初步分析  

Preliminary Analysis of Lower Respiratory Tract Infection in Infants and Children Caused by Chlamydia Trachomatis

作　　者：周雪原 庞晓燕 李灵 李璐 宋月欣 王晓华 ZHOU Xue-yuan;PANG Xiao-yan;LI Ling(Department of Genetic and Orthogenics,Inner Mongolia Maternal and Child Care Hospital,Huhhot,Inner Mongolia,010010,China)

机构地区：[1]内蒙古自治区妇幼保健院遗传优生科,内蒙古呼和浩特010010

出　　处：《黑龙江医学》2023年第1期50-52,共3页Heilongjiang Medical Journal

摘　　要：目的:分析沙眼衣原体(CT)致婴幼儿下呼吸道感染情况,为临床快速诊断CT肺炎提供有力数据支撑。方法:采用荧光聚合酶链式反应(PCR)方法对婴幼儿咽拭子、痰液、肺泡灌洗液等样本进行特异性DNA核酸片段检测,对2019年10月1日—2021年1月30日内蒙古自治区妇幼保健院儿科病房和新生儿病房收治的410例下呼吸道炎症患儿进行CT核酸检测筛查,并将阳性病例按不同月龄进行统计分析,探讨CT引起不同月龄婴幼儿下呼吸道感染情况。结果:410例下呼吸道感染婴幼儿中,阳性23例,阳性率为5.61%。1月龄婴幼儿检测33例,阳性3例,阳性率为9.1%;2月龄婴幼儿检测112例,阳性14例,阳性率为12.5%;3月龄婴幼儿检测74例,阳性4例,阳性率为5.41%;3月龄以上婴幼儿检测191例,阳性2例,阳性率为1.05%。结论:CT感染婴幼儿肺炎在临床诊疗中不容忽视,进行肺部感染婴幼儿呼吸道、孕前体检和孕期生殖道CT筛查必不可少。Objective:To analyse the infection of Chlamydia trachomatis pneumonia infant and provide data for the diagnosis of CT pneumonia.Methods:Fluorescence polymerase chain reaction(PCR)was used to detect the specific DNA fragments of in⁃fant throat swabs,sputum and alveolar lavage fluid.410 children admitted to the hospital with lower respiratory tract inflammation from October 1,2019 to January 30,2021 were screened for Chlamydia trachomatis nucleic acid testing.The positive cases were al⁃so statistically analyzed by different months of age to explore the lower respiratory tract infection caused by Chlamydia trachomatis in infants and children of different months of age.Results:Of 410 infants and children with lower respiratory tract infections,23 were positive,with a positive rate of 5.61%.There were 33 positive cases in 1 month old infants and 3 positive cases,with a posi⁃tive rate of 9.1%.112 positive cases in 2 month old infants and 14 positive cases,with a positive rate of 12.5%.74 positive cases in 3 month old infants and 4 positive cases,with a positive rate of 5.41%.191 positive cases in 3 month old and above,with a posi⁃tive rate of 1.05%.Conclusion:Chlamydia trachomatis infection in infants and children with pneumonia should not be neglected in clinical practice,and screening for Chlamydia trachomatis in infants and children with lung infection respiratory tract,pre-preg⁃nancy physical examination and reproductive tract during pregnancy is essential.

关 键 词：沙眼衣原体 婴幼儿 肺炎 

分 类 号：R722.135[医药卫生—儿科]