Detection and localization of the hemoglobin and collagen distribution of the uterine cervix  

作　　者：Tran Van Tien Nguyen Ngoc Quynh Le Huynh Duc Phan Ngoc Khuong Cat Huynh Quang Linh 

机构地区：[1]Department of Applied Physics,Faculty of Applied Science Ho Chi Minh City University of Technology,700000 Vietnam [2]DCSELAB—National key Laboratory of Digital Control and System Engineering,700000 Vietnam [3]Department of Biomedical Engineering,Faculty of Medicine Nguyen Tat Thanh University,700000 Vietnam [4]Department of Engineering Physics,Faculty of Applied Science Ho Chi Minh City University of Technology,700000 Vietnam

出　　处：《Journal of Innovative Optical Health Sciences》2019年第4期116-126,共11页创新光学健康科学杂志（英文）

基　　金：supported by National Key Laboratory of Digital Control and System Engineering,and the Department of Biomedical Engineering,HCMUT-VNU HCM.

摘　　要：Changes of the blood vessels and collagen are associated with the development of abnormal cervical cells.Recently,optical coberence tomography and Mueller polarization images were 1used to provide information regarding the presence of collagen fibers in the cervical tissue.However,most of these methods need a lot of time for image recording and are expensive.In addition,the general survey on the absorption and distribution characteristics of collagen and blood in the cervical is still lacking.In this study,we developed a colposcopy combining cross-polarized inage and image procssing algorithm with an fficient analytical model to map the distribution of blood and collagen in the uterine.For this system's proof of concept,we captured and processed the case of cervical ectopy and Nabothian cyst.The results show that the distribution of blood and collagen maps matched with anatomical and physiological when compared with Lugol's iodline images.This technology has some advantages,such as low cost,real time,and can replace the 11se of acetic acid or Lugol's iodine in the future.

关 键 词：HEMOGLOBIN COLLAGEN cross polarized image uterine cervix 

分 类 号：R318[医药卫生—生物医学工程]