Multi-frame speckle reduction in OCT using supercontinuum pumped by noise-like pulses  

作　　者：Chengming Wang Yi-Jing You Shengnan Ai Wenxin Zhang Wenchao Liao Xiao Zhang Juicheng Hsieh Ning Zhang Bihua Tang Ci-Ling Pan Ping Xue 

机构地区：[1]State Key Laboratory of Low-Dimensional Quantum Physics Department of Physics,Tsinghua University Collaborative Innovation Center of Quantum Matter Beijing,P.R.China [2]Department of Physics,National Tsing Hua University No.101,Sec.2,Kuang-Fu Rd,Hsinchu,Taiwan [3]Department of Physics and Institute of Photonics Technologies National Tsing Hua University,Taiwan [4]School of Life Science Beijing Institute of Technology,Beijing,P.R.China [5]Institute of Forensic Science Ministry of Public Security Beijing,P.R.China [6]Southwest Medical University Luzhou,Sichuan Province,P.R.China [7]Nuctech Company Limited,Beijing,P.R.China

出　　处：《Journal of Innovative Optical Health Sciences》2019年第2期86-92,共7页创新光学健康科学杂志（英文）

基　　金：This research was supported by the National Natural Science Foundation of China(61227807,61575108 and 61505034);Tsinghua Initiative Scientific Research Program(2013THZ02-3);C.L.Pan and Y.J.You were supported in part by the Ministry of Science and Technology,Taiwan,under Grant 103-2622-E-007-006-CC2 and by the National Tsing Hua University Research Program Grant 104N2711E1.C.L.Pan is also supported by the Air Force Office of Scientific Research FA2386-13-1-4086.The first three authors contribute equally to this paper。

摘　　要：In most coherent imaging modality,speckle noise is a major cause that blurs the boundary of tissues and degrades the image contrast.By utilizing the unique properties of supercontinuum(SC)generated by noise-like pulses(NLPs)and a simple multi-frame averaging technique,we achieved significant speckle reduction in spectral domain optical coherence tomography(SD-OCT).We quantitatively compared the speckle of our proposed method with those of conventional swept source OCT(SS-OCT)and SD-OCT based on commercial light sources.The experimental results show that SC pumped by NLPs combined with noncoherent averaging method achieves better denoising performance in terms of contrast to noise ratio(CNR).

关 键 词：Noise-like pulses supercontinuum generation speckle reduction optical coherence tomography 

分 类 号：O43[机械工程—光学工程]