Nitrene-Mediated P-N Coupling Under Iron Catalysis  

作　　者：Ziqian Bai Fangfang Song Hao Wang Wangxing Cheng Shiyang Zhu Yi Huang Gang He Gong Chen 

机构地区：[1]State Key Laboratory and Institute of Elemento-Organic Chemistry,College of Chemistry,Nankai University,Tianjin 300071

出　　处：《CCS Chemistry》2022年第7期2258-2266,共9页中国化学会会刊（英文）

基　　金：the Natural Science Foundation of China(nos.21421062 and 21901127);the China Postdoctoral Science Foundation(nos.2018M640225 and 2019T120179);Nankai-Cangzhou Green Chemistry Institute(no.NCC2020FH02)for financial support of this work.

摘　　要：P-N and P=N bonds play important roles in the design and synthesis of functional molecules such as bioactive compounds and organic ligands for catalysis.Existing methods for P-N coupling mostly rely on Staudinger condensation or nucleophilic substitution between phosphorus electrophiles and amine nucleo philes.Herein,we report a nitrene-mediated intermolecular P-N coupling reaction between various phos phorus nucleophiles and dioxazolones under simp le iron-catalyzed conditions.These reactions offer an efficient,versatile,and broadly applicable method for synthesis of a range of N-P compounds,including amidophosphines,iminophosphonamides,phosphinamides,aminophosphines,and iminophospho ranes,from readily available precursors under mild conditions.

关 键 词：imidation nitrenoid phosphorus chemistry iron catalysis 

分 类 号：O62[理学—有机化学]