钛合金植入物对椎体放射治疗计划的剂量学影响  

Dosimetric Impact of Titanium Alloy Implant in Spinal IMRT Plan

作　　者：陈晓慧[1,2,3,4] 许安杰 陈佳艳[1,2,3,4] 胡伟刚 彭佳元[1,2,3,4] CHEN Xiaohui;XU Anjie;CHEN Jiayan;HU Weigang;PENG Jiayuan(Department of Radiation Oncology,Fudan University Shanghai Cancer Center,Shanghai,200032;Department of Oncology,Shanghai Medical College,Fudan University,Shanghai,200032;Shanghai Key Laboratory of Radiation Oncology,Shanghai,200032;Shanghai Clinical Research Center for Radiation Oncology,Shanghai,200032)

机构地区：[1]复旦大学附属肿瘤医院放射治疗中心,上海市200032 [2]复旦大学上海医学院肿瘤学系,上海市200032 [3]上海市放射肿瘤学重点实验室,上海市200032 [4]上海市放射治疗临床医学研究中心,上海市200032

出　　处：《中国医疗器械杂志》2023年第1期110-114,共5页Chinese Journal of Medical Instrumentation

摘　　要：该研究的目的是在含有钛合金植入物的椎体放射治疗计划中应用一种校正方法,修正CT密度表以包含钛金属的CT密度信息。通过比较调强计划在应用校正方法前后的剂量分布改变,以及在含有椎体固定装置的自制仿真模体上验证计算剂量来研究相应剂量学影响。结果显示在IMRT计划中应用校正方法后脊髓最大剂量有明显改变,且校正方法降低了计算结果与实际测量的偏差。研究证明该校正方法可以减小剂量计算时的剂量误差。The purpose of this study is to establish and apply a correction method for titanium alloy implant in spinal IMRT plan,a corrected CT-density table was revised from normal CT-density table to include the density of titanium alloy implant.Dose distribution after and before correction were calculated and compared to evaluate the dose deviation.Plans were also copied to a spinal cancer simulation phantom.A titanium alloy fixation system for spine was implanted in this phantom.Plans were recalculated and compared with the measurement result.The result of this study shows that the max dose of spinal cord showed significant difference after correction,and the deviation between calculation results and measurement results was reduced after correction.The method for expanding the range CT-density table,which means that the density of titanium alloy was included,can reduce the error in calculation.

关 键 词：椎体转移 钛合金植入物 调强放射治疗 剂量学 

分 类 号：R815[医药卫生—放射医学]