Nickel-Catalyzed Cross-Electrophile Vinyl–Vinyl Coupling:An Approach to Structurally Versatile Dienylboronates  

作　　者：Guang-Li Xu Chun-Yan Liu Xiaobo Pang Xue-Yuan Liu Xing-Zhong Shu 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry(SKLAOC),College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000

出　　处：《CCS Chemistry》2022年第3期864-871,共8页中国化学会会刊（英文）

基　　金：The authors thank the National Natural Science Foundation of China for financial support(nos.21772072 and 22071084)。

摘　　要：Cross C–C bond formation of two vinyl electrophiles is a long-standing challenge in synthetic chemistry.Herein,we report a nickel-catalyzed reductive vinyl–vinyl coupling between vinyl triflates and boron-substituted vinyl bromides.This new protocol offers facile access to dienylboronates with high structural complexity and molecular diversity.The reaction proceeds with a broad substrate scope under very mild conditions.The synthetic utility of the method is highlighted by its gram-scale reaction,modification of complex molecules,and diverse transformation of the products.

关 键 词：nickel boron DIENES CROSS-COUPLING reductive coupling 

分 类 号：O62[理学—有机化学]