Power spectral density-based nearinfrared sub-band detection for noninvasive blood glucose prediction in both in-vitro and in-vivo studies  

作　　者：Ibrahim Akkaya 

机构地区：[1]Izmir Biomedicine and Genome Center(iBG)Balcova,Izmir 35340,Turkey [2]Erman Selim,Mert Altintas and Mehmet Engin Electrical Electronics Engineering Department Ege University,Bornova,Izmir 35040,Turkey

出　　处：《Journal of Innovative Optical Health Sciences》2018年第6期43-54,共12页创新光学健康科学杂志（英文）

基　　金：The Scientic and Technological Research Council of Turkey(TUBITAK)under Grant No.113E610.

摘　　要：Diabetes is a widespread and serious disease and noninvasive measurement has been in high demand.To address this problem,a power spectral density-based method was offered for determining glucose sensitive sub-bands in the nearinfrared(NIR)spectrum.The experiments were conducted using phantoms of different optical properties in-vitro conditions.The optical bands 1200–1300 nm and 2100–2200 nm were found feasible for measuring blood glucose.After that,a photoplethysmography(PPG)-based low cost and portable optical system was designed.It has six di®erent NIR wavelength LEDs for illumination and an InGaAs photodiode for detection.Optical density values were calculated through the system and used as independent variables for multiple linear regression analysis.The results of blood glucose levels for 24 known healthy subjects showed that the optical system prediction was nearly 80%in the A zone and 20%in the B zone according to the Clarke Error Grid analysis.It was shown that a promising easyuse,continuous,and compact optical system had been designed.

关 键 词：NONINVASIVE blood glucose nearinfrared led PHOTOPLETHYSMOGRAPHY power density 

分 类 号：TN3[电子电信—物理电子学]