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作 者:李婷 刘朝晖 LI Ting;LIU Zhaohui(Department of Gynecology,Beijing Obstetrics and Gynecology Hospital,Capital Medical UniversityBeijing Maternal and Child Health Care Hospital,Beijing100026,China)
机构地区:[1]首都医科大学附属北京妇产医院北京妇幼保健院妇科,北京100026
出 处:《中国医药导报》2023年第3期88-92,共5页China Medical Herald
基 金:国家自然科学基金资助项目(81771530、81801406)。
摘 要:盆腔炎性疾病(PID)是育龄期女性常见的疾病之一,可导致输卵管性不孕、异位妊娠及慢性盆腔痛等后遗症,对女性生殖健康造成重大危害。2021年美国疾病控制和预防中心(CDC)发布了《2021年性传播疾病治疗指南》(以下简称“2021年CDC指南”),完成了对《2015年性传播疾病治疗指南》(以下简称“2015年CDC指南”)的重要更新,大多数PID症状及体征较轻或隐匿,故诊断仍然依靠临床最低标准,治疗以采用覆盖所有可能致病菌的广谱、经验性抗菌药物为主,强调加用甲硝唑覆盖厌氧菌,不同静脉及非静脉药物方案均表现出良好的效果。本文比较了2021年CDC指南、2015年CDC指南及我国《盆腔炎症性疾病诊治规范(2019修订版)》的相关内容,以期对我国现阶段PID临床实践工作提供参考和帮助。Pelvic inflammatory disease(PID) is one of the common diseases of women of childbearing age, which can lead to sequelae such as tubal infertility, ectopic pregnancy, and chronic pelvic pain, and cause great harm to female reproductive health. In 2021, the Centers for Disease Control and Prevention(CDC) issued Sexually Transmitted Infections Treatment Guidelines, 2021(“2021 CDC guidelines”for short), completing a significant update to Sexually Transmitted Diseases Treatment Guidelines, 2015(“2015 CDC guidelines”for short), most of the symptoms and signs of PID are mild or latent, so the diagnosis still relies on the minimum clinical standards. The treatment is mainly based on the use of broad spectrum,empirical antibiotics covering all possible pathogens, emphasizing the addition of metronidazole to cover anaerobic bacteria.Different intravenous and non-intravenous drug regimens have shown good efficacy. This paper compares the 2021 CDC guidelines, 2015 CDC guidelines, and Chinese Guidelines for Diagnosis and Treatment of Pelvic Inflammatory Diseases(2019 Revision), in order to provide reference and help for the current clinical practice of PID in China.
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