盆腔粘连松解术及输卵管伞端造口术治疗盆腔炎致不孕症的效果  

Effect of pelvic adhesiolysis combined with salpingostomy in the treatment of infertility caused by pelvic inflammation disease

作　　者：吴淋淋[1] 徐浩[2] 李池慧 WU Linlin;XU Hao;LI Chihui(Department of Gynecology,Jinhua People’s Hospital,Zhejiang Province,Jinhua321000,China;Department of Clinical Laboratory,Jinhua Central Hospital,Zhejiang Province,Jinhua321000,China;Department of Clinical Laboratory,Jinhua People’s Hospital,Zhejiang Province,Jinhua321000,China)

机构地区：[1]浙江省金华市人民医院妇科,浙江金华321000 [2]浙江省金华市中心医院检验科,浙江金华321000 [3]浙江省金华市人民医院检验科,浙江金华321000

出　　处：《中国医药导报》2023年第2期76-79,共4页China Medical Herald

基　　金：浙江省金华市科技计划项目(2020-3-056);浙江省医药卫生科技计划项目(2021KY1184)。

摘　　要：目的 观察腹腔镜下盆腔粘连松解术及输卵管伞端造口术治疗盆腔炎所致不孕症的临床效果。方法 选择2019年8月至2020年11月浙江省金华市人民医院慢性盆腔炎致不孕症的育龄期妇女100例。根据随机数字表法将其分为观察组和对照组,每组50例。对照组接受宫腔镜下输卵管通液术治疗,观察组在对照组治疗基础上,接受腹腔镜下盆腔粘连松解术及输卵管伞端造口术治疗。比较两组治疗前后血清促卵泡激素(FSH)、黄体生成素(LH)、雌二醇(E_(2))水平;随访1年,比较两组自然受孕率、异位妊娠率。结果 治疗后,两组FSH较治疗前下降,E_(2)较治疗前上升;观察组FSH低于对照组,E_(2)高于对照组(P<0.05)。治疗前后,两组LH比较,差异无统计学意义(P>0.05)。观察组自然受孕率高于对照组(P<0.05);两组异位妊娠率比较,差异无统计学意义(P>0.05)。结论 盆腔炎导致不孕症患者在输卵管通液术基础上采用经腹腔镜盆腔粘连松解术及输卵管伞端造口术治疗,可以获得更为理想的临床效果。Objective To observe the clinical effect of laparoscopic pelvic adhesiolysis combined with salpingostomy in the treatment of infertility caused by pelvic inflammatory disease.Methods From August 2019 to November 2020,a total of 100women of infertility caused by chronic pelvic inflammatory disease in childbearing age were selected.They were divided into observation group and control group according to the random number table,with 50 cases in each group.The control group was accepted with hysteroscopic hydrotubation therapy,and observation group was treated by laparoscopic pelvic adhesiolysis combined with salpingostomy on the basis of the control group.Serum follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_(2)) between two groups before and after treatment were compared;1-year follow-up,the natural conception rate and ectopic pregnancy rate were compared between two groups.Results After treatment,FSH decreased and E_(2) increased in both groups compared with before treatment;FSH in observation group was lower than that in control group,E_(2) was higher than that in control group(P<0.05).There were no significant differences in LH between two groups before and after treatment (P>0.05).The natural conception rate of observation group was higher than that of control group(P<0.05);there was no significant difference in the incidence of ectopic pregnancy between two groups (P>0.05).Conclusion In the treatment of infertile patients caused by pelvic inflammatory disease,more ideal clinical effect can be obtained by laparoscopic pelvic adhesiolysis combined with salpingostomy on the basis of hydrotubation.

关 键 词：腹腔镜 盆腔粘连松解术 输卵管伞端造口术 慢性盆腔炎 不孕症 

分 类 号：R71[医药卫生—妇产科学]