李双蕾教授从肾虚络瘀探析糖尿病性骨质疏松症经验  

Professor Li Shuanglei’s experience on diabetic osteoporosis from kidney deficiency and blood stasis in collaterals

作　　者：董丽萍 唐爱华[2] 李双蕾[1] 周烨鑫 赖楚楚 张晓婷 DONG Liping;TANG Aihua;LI Shuanglei;ZHOU Yexin;LAI Chuchu;ZHANG Xiaoting(Guangxi University of Chinese Medicine,Guangxi Zhuang Autonomous Region,Nanning530000,China;Department of Endocrinology,the First Affiliated Hospital of Guangxi University of Chinese Medicine,Guangxi Zhuang Autonomous Region,Nanning530023,China)

机构地区：[1]广西中医药大学,广西南宁530000 [2]广西中医药大学第一附属医院内分泌科,广西南宁530023

出　　处：《中国医药导报》2023年第2期135-138,143,共5页China Medical Herald

基　　金：国家自然科学基金地区科学基金项目(81860784);广西名老中医民族医传承工作室建设项目(桂卫中〔2014〕9号)。

摘　　要：糖尿病性骨质疏松症作为一种全身性骨代谢疾病,是糖尿病的重要并发症,也一直是临床的重难点。李双蕾教授是广西名中医,通过多年的临床实践与观察,在防治糖尿病性骨质疏松症方面经验丰富。消渴日久,虚实夹杂,肾虚骨络失养,肾主骨生髓功能降低则骨枯髓减发为“骨痿”;消渴日久,久病入络则瘀血瘀阻肾络,伏瘀伤骨,可进一步加速骨骼的损伤,形成恶性循环。李双蕾教授首先提出糖尿病性骨质疏松症的核心病机是肾虚血瘀、骨络受损,治疗当以补肾化瘀为主要原则。李双蕾教授根据壮骨方进行加减应用,对于糖尿病性骨质疏松症的临床诊治,取得了较好的实践效果。李双蕾教授着重从肾虚络瘀的致病特点出发,分析肾虚络瘀与糖尿病性骨质疏松症发病的关系,期望从不同的角度为临床论治糖尿病性骨质疏松症提供理论依据。As a systemic bone metabolic disease,diabetic osteoporosis is an important complication of diabetes,and has always been a difficult clinical problem.Professor Li Shuanglei is a famous traditional Chinese medicine doctor in Guangxi Zhuang Autonomous Region.Through many years of clinical practice and observation,Professor Li Shuanglei has rich experience in the prevention and treatment of diabetic osteoporosis.When consumptive thirst is dissipated for a long time,deficiency and excess are mixed,the kidney is deficient and the bone collateral is lost of nutrition,and the kidney dominating bone marrow function is reduced,and bone is withered and marrow is reduced,and then reduced to become“bone flaccid”;when consumptive thirst is dissipated for a long time,long disease into the collaterals,blood stasis blocks the kidney collaterals,blood stasis damages bone,which can further accelerate the bone damage,the formation of a vicious cycle.Professor Li Shuanglei first proposed that the core pathogenesis of diabetic osteoporosis is kidney deficiency and blood stasis in collaterals,and bone collateral damage,and the treatment should take tonifying kidney and removing blood stasis as the main principle.Professor Li Shuanglei makes addition and subtraction application according to Zhuanggu Formula,and achieves good practical results in the clinical diagnosis and treatment of diabetic osteoporosis.Based on the pathogenic characteristics of kidney deficiency and blood stasis in collaterals,Professor Li Shuanglei analyzes the relationship between kidney deficiency and blood stasis in collaterals and the incidence of diabetic osteoporosis,hoping to provide theoretical basis for clinical treatment of diabetic osteoporosis from different perspectives.

关 键 词：肾虚络瘀 糖尿病性骨质疏松症 病因病机 治法 中医中药 

分 类 号：R587.1[医药卫生—内分泌]