含氟芳香族化合物的合成方法与进展  

Synthetic Methods and Progress of Fluoroaromatic Compounds

作　　者：周华东 贝宏 韩庆 王海 ZHOU Huadong;BEI Hong;HAN Qing;WANG Hai(Zhejiang Quhua Fluor-Chemistry Co.,Ltd.,Quzhou 324004,China;Zhejiang Kaisn Fluorochemical Co.,Ltd.,Quzhou 324004,China)

机构地区：[1]浙江衢化氟化学有限公司,浙江衢州324004 [2]浙江凯圣氟化学有限公司,浙江衢州324004

出　　处：《有机氟工业》2022年第4期25-29,共5页Organo-Fluorine Industry

摘　　要：含氟芳香族化合物具有独特的性质,被广泛应用于医药、农药和染料等领域。如何将氟原子引入至芳香族化合物的特定部位从而改变和提高化合物的独特活性已经成为新产品研究开发的热点,如何高效地实现C—F键的构建也是目前研究的重点。综述了含氟芳香族化合物的常用合成方法以及最新进展,并对各种合成方法进行了比较。The unique properties of fluoroaromatic compounds are widely used in medicine,pesticides,dyes and other fields.How to introduce fluorine atoms into specific parts of aromatic compounds to change and improve the unique activity of compounds has become a hot spot in the research and development of new products.How to efficiently realize the construction of C—F bonds is also the focus of current research.The common synthetic methods of fluoroaromatic compounds and the latest progress of synthetic methods are reviewed,and various synthetic methods are compared.

关 键 词：含氟芳香族化合物 氟化剂 氟化反应 

分 类 号：TQ242[化学工程—有机化工]