Mechanical Trapping of the Phlorin Intermediate  

作　　者：Min Tang Yimin Liang Jiali Liu Lifang Bian Zhichang Liu 

机构地区：[1]Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province,School of Science,Westlake University,and Westlake Institute for Advanced Study,Hangzhou,Zhejiang 310024

出　　处：《CCS Chemistry》2022年第10期3230-3237,共8页中国化学会会刊（英文）

基　　金：from the National Natural Science Foundation of China(grant nos.22171232 and 21971211);the Natural Science Foundation of Zhejiang Province(grant no.2022XHSJJ007);the Qiantang River Talent Foundation(grant no.QJD1902029).

摘　　要：Trapping unstable intermediates for elucidating reaction mechanisms in chemistry presents a formidable challenge.There has long been a lack of direct evidence for key intermediates like the highly reactive phlorin leading to porphyrin.Here,we report a molecular-strain engineering(MSE)strategy that harnesses intramolecular strain to trap the native phlorin during porphyrin synthesis.By mechanically constraining its periphery,a phlorin stable towards oxidation was captured as an isolable intermediate and fully characterized.

关 键 词：molecular-strain engineering molecular bows porphyrinogens PORPHYRINS proton-coupled electrontransfer photoinducedoxidativearomatization reaction mechanism 

分 类 号：O62[理学—有机化学]