Exploration of Oxidative Ritter-Type Reaction ofα-Arylketones and Its Application for the Collective Total Syntheses of Erythrina Alkaloids  

作　　者：Meng-En Chen Shi-Zhong Tang Yue-Hong Hu Qin-Tong Li Zhang-Yan Gan Jian-Wei Lv Fu-Min Zhang 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry,College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000

出　　处：《CCS Chemistry》2022年第10期3378-3390,共13页中国化学会会刊（英文）

基　　金：the NSFC(grant nos.21971095,21772076,and 91956203.)for financially supporting this work.

摘　　要：Although the classical Ritter reaction has beenwidely applied to prepare sterically hindered amides since 1948,it has intrinsic problems,such as harsh reaction conditions,the multistep preparation of synthetic precursors,and the use of solvent quantities of nitrile.In particular,only a few examples of the total synthesis of natural products using the Ritter reaction as a key step have been reported to date.

关 键 词：oxidative Ritter-type reaction sterically hindered amide erythrina alkaloids collective total syntheses protecting-group free procedure 

分 类 号：O62[理学—有机化学]