硝菔增液汤治疗急性缺血性脑卒中后便秘的临床效果观察  

Clinical observation of Xiaofu Zengye Decoction in the treatment of post-acute cerebral infarction constipation

作　　者：任江[1] REN Jiang(Shenyang Second Hospital of Traditional Chinese Medicine,Shenyang 110101,China)

机构地区：[1]沈阳市第二中医医院,110101

出　　处：《中国现代药物应用》2023年第2期147-149,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨硝菔增液汤治疗急性缺血性脑卒中后便秘的临床效果。方法60例急性缺血性脑卒中后便秘患者,按照入院编号单双数分为中药组(单数)和对照组(双数),各30例。中药组使用硝菔增液汤治疗,对照组使用乳果糖口服溶液治疗。比较两组患者治疗前后改良Barthel指数评定量表(MBI)评分、便秘患者生活质量量表(PAC-QOL)评分、中医症状积分以及停药后30d复发情况。结果治疗后,两组患者MBI、PAC-QOL评分均优于治疗前,且中药组患者MBI评分(83.13±10.75)分、PAC-QOL评分(33.79±9.47)分均优于对照组的(75.27±14.43)、(40.88±13.41)分,差异均具有统计学意义(P<0.05)。中药组患者治疗后中医症状积分(11.86±4.33)分、停药后30d复发率10.00%均低于对照组的(16.56±5.22)分、36.67%,差异均具有统计学意义(P<0.05)。结论硝菔增液汤治疗急性缺血性脑卒中后便秘具有快速通便、无毒高效的作用,且无明显依赖性,有利于患者预后恢复。Objective To discuss the clinical effect of Xiaofu Zengye Decoction in the treatment of post-acute cerebral infarction constipation.Methods A total of 60 patients with post-acute cerebral infarction constipation were divided into traditional Chinese medicine group(odd number)and control group(even number)according to the admission number,with 30 patients in each group.The traditional Chinese medicine group was treated with Xiaofu Zengye Decoction,and the control group was treated with lactulose oral solution.Both groups were compared in terms of modified Barthel index(MBI)score,patient assessment of constipation quality of life(PAC-QOL)score,traditional Chinese medicine symptom score and the recurrence at 30 d after drug withdrawal.Results After treatment,the MBI and PAC-QOL scores of both groups were better than those of this group before treatment;the MBI score(83.13±10.75)points and PAC-QOL score(33.79±9.47)points in the traditional Chinese medicine group were better than(75.27±14.43)and(40.88±13.41)points in the control group;the differences were statistically significant(P<0.05).In the traditional Chinese medicine group,the traditional Chinese medicine symptom score was(11.86±4.33)points after treatment,and the recurrence rate was 10.00%at 30 d after drug withdrawal,which were lower than(16.56±5.22)points and 36.67%in the control group,and the differences were all statistically significant(P<0.05).Conclusion Xiaofu Zengye Decoction for the treatment of post-acute cerebral infarction constipation has rapid effect on relaxing the bowels.It is non-toxic and efficient without obvious dependence,and is conducive to prognosis and recovery of patients.

关 键 词：硝菔增液汤 急性缺血性脑卒中 便秘 生活质量 

分 类 号：R277.7[医药卫生—中医学] R256.35