关节镜下微骨折术联合富血小板血浆治疗膝关节软骨损伤的临床效果  

Clinical effect of arthroscopic microfracture combined with platelet-rich plasma in the treatment of articular cartilage injury of knee

作　　者：叶栋[1] 廖学勤[1] 简蔚泓[1] 冯捷 骆淑玲 万悦 江丽兵 YE Dong;LIAO Xue-qin;JIAN Wei-hong(Nanchang First Hospital,Nanchang 330000,China)

机构地区：[1]南昌市第一医院,330000

出　　处：《中国实用医药》2023年第2期20-23,共4页China Practical Medicine

基　　金：江西省卫生健康委科技计划项目(20204035)。

摘　　要：目的探讨关节镜下微骨折术联合富血小板血浆(PRP)治疗膝关节软骨损伤的临床效果。方法120例膝关节软骨损伤患者,通过双盲法随机分为实验组和对照组,每组60例。实验组选择关节镜下微骨折术联合富血小板血浆疗法,对照组采用关节镜下微骨折术联合玻璃酸钠注射液疗法。对比两组患者并发症发生情况及手术前后疼痛情况、膝关节功能评分、关节平衡功能评分。结果术后1、6个月,实验组视觉模拟评分法(VAS)评分分别为(4.33±0.74)、(2.46±0.47)分,均显著低于对照组的(4.68±0.51)、(2.69±0.55)分,差异具有统计学意义(P<0.05)。术后1、6个月,实验组Lysholm膝关节评分分别为(79.65±4.99)、(89.62±3.36)分,均显著高于对照组的(76.98±4.64)、(87.69±3.29)分,差异具有统计学意义(P<0.05)。术后1、6个月,实验组关节平衡功能评分分别为(45.32±3.33)、(53.67±3.64)分,均显著高于对照组的(43.25±3.12)、(51.26±4.02)分,差异具有统计学意义(P<0.05)。实验组并发症发生率3.33%低于对照组的8.33%,但差异无统计学意义(P>0.05)。结论对膝关节软骨损伤患者采用关节镜下微骨折术联合富血小板血浆注射治疗,能够有效改善患者的关节平衡功能、膝关节功能,减轻患者的疼痛感,且安全性高,值得临床广泛的推广与应用。Objective To discuss the clinical effect of arthroscopic microfracture combined with plateletrich plasma(PRP)in the treatment of articular cartilage injury of knee.Methods A total of 120 patients with articular cartilage injury of knee were randomly divided into experimental group and control group by double-blind method,with 60 cases in each group.The experimental group was treated with arthroscopic microfracture surgery and platelet-rich plasma therapy,while the control group was treated with arthroscopic microfracture surgery and sodium vitrate injection therapy.The occurrence of complications,and the pain,knee function score and joint balance function score before and after surgery were compared between the two groups.Results At 1 and 6 months after surgery,the visual analogue scale(VAS)scores of the experimental group were(4.33±0.74)and(2.46±0.47)points,which were significantly lower than(4.68±0.51)and(2.69±0.55)points of the control group,and the differences were statistically significant(P<0.05).At 1 and 6 months after surgery,the Lysholm knee scores of the experimental group were(79.65±4.99)and(89.62±3.36)points,which were significantly higher than(76.98±4.64)and(87.69±3.29)points of the control group,and the differences were statistically significant(P<0.05).At 1 and 6 months after surgery,the joint balance function scores of the experimental group were(45.32±3.33)and(53.67±3.64)points,which were significantly higher than(43.25±3.12)and(51.26±4.02)points of the control group,and the differences were statistically significant(P<0.05).The complication rate 3.33%in the experimental group was lower than 8.33%in the control group,but the difference was not statistically significant(P>0.05).Conclusion The use of arthroscopic microfracture surgery combined with platelet-rich plasma injection in patients with articular cartilage injury of knee can effectively improve the patient's joint balance function and knee joint function,reduce the patient's pain.It has high safety,and is worthy of wide clinica

关 键 词：关节镜 微骨折术 富血小板血浆 膝关节软骨损伤 

分 类 号：R687.4[医药卫生—骨科学]