Whole-genome resequencing reveals recent signatures of selection in five populations of largemouth bass(Micropterus salmoides)  

作　　者：Cheng-Fei Sun Xin-Hui Zhang Jun-Jian Dong Xin-Xin You Yuan-Yuan Tian Feng-Ying Gao He-Tong Zhang Qiong Shi Xing Ye 

机构地区：[1]Key Laboratory of Tropical and Subtropical Fishery Resources Application and Cultivation,Ministry of Agriculture and Rural Affairs,Pearl River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Guangzhou,Guangdong 510380,China [2]Shenzhen Key Lab of Marine Genomics,Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals,BGI Academy of Marine Sciences,BGI Marine,Shenzhen,Guangdong 518081,China [3]College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Zoological Research》2023年第1期78-89,共12页动物学研究（英文）

基　　金：supported by the Key-Area Research and Development Program of Guangdong Province(2021B0202020001);China Agriculture Research System of MOF and MARA(CARS-46);Central Public-interest Scientific Institution Basal Research Fund of CAFS(2020TD23,2020ZJTD-02);Project of Construction of Guangdong Aquatic Seed Industry Demonstration Base 2021;Special Funds for Science Technology Innovation and Industrial Development of Shenzhen Dapeng New District(KJYF202101-02)。

摘　　要：Largemouth bass(Micropterus salmoides) is an economically important fish species in North America, Europe, and China. Various genetic improvement programs and domestication processes have modified its genome sequence through selective pressure, leaving nucleotide signals that can be detected at the genomic level. In this study,we sequenced 149 largemouth bass fish, including protospecies(imported from the US) and improved breeds(four domestic breeding populations from China). We detected genomic regions harboring certain genes associated with improved traits, which may be useful molecular markers for practical domestication, breeding, and selection. Subsequent analyses of genetic diversity and population structure revealed that the improved breeds have undergone more rigorous genetic changes. Through selective signal analysis, we identified hundreds of putative selective sweep regions in each largemouth bass line. Interestingly, we predicted 103 putative candidate genes potentially subjected to selection,including several associated with growth(psst1 and grb10), early development(klf9, sp4, and sp8), and immune traits(pkn2, sept2, bcl6, and ripk2). These candidate genes represent potential genomic landmarks that could be used to improve important traits of biological and commercial interest. In summary, this study provides a genome-wide map of genetic variations and selection footprints in largemouth bass, which may benefit genetic studies and accelerate genetic improvement of this economically important fish.

关 键 词：Largemouth bass Whole-genome resequencing Signatures of selection Growth Immunity 

分 类 号：Q943.2[生物学—植物学]