不规则抗体在输血前患者中的筛查价值  

Value of Screening for Irregular Antibodies in Pre-transfusion Patients

作　　者：孔彬[1] KONG Bin(Department of Laboratory,Yixing People's Hospital of Jiangsu Province,Yixing,Jiangsu Province,214200 China)

机构地区：[1]江苏省宜兴市人民医院检验科,江苏宜兴214200

出　　处：《系统医学》2022年第21期106-109,共4页Systems Medicine

摘　　要：目的 探索和分析不规则抗体在输血前患者中的临床筛查价值。方法 选取2018年4月—2021年4月期间于宜兴市人民医院进行计划输血和手术备血的患者16 273例作为研究对象,在患者进行交叉配血前,使用微柱凝胶抗人球蛋白卡检测方法对输血前患者进行不规则抗体的检测以及筛查,分析年龄、性别、妊娠史及输血史对不规则抗体产生的影响。结果 16 273例患者中共发现50例不规则抗体阳性患者,不规则抗体阳性率为0.31%;在不同年龄段的患者中,41~60岁输血前患者检测的阳性率最高,达到0.37%,而>80岁患者阳性率最低,为0.18%;在不同性别的患者中,女性患者不规则抗体阳性率要高于男性患者,分别为0.36%和0.23%;在不同输血史及妊娠史的患者中,有输血史患者的不规则抗体阳性率要高于无输血史患者,另外有妊娠史患者的不规则抗体阳性率高于无妊娠史患者。结论 输血前患者的不规则抗体阳性率较高,其中41~60岁患者、女性患者、有输血史和妊娠史患者的不规则抗体阳性率较高,因此该类患者输血前进行不规则抗体筛查非常有必要。Objective To explore and analyze the clinical screening value of irregular antibodies in pre-transfusion patients. Methods 16 273 patients with planned blood transfusion and surgical blood preparation who were admitted to Yixing People’s Hospital from April 2018 to April 2021 were selected as the research objects. Before cross matching, irregular antibodies were detected and screened in patients before blood transfusion using microcolumn gel anti human globulin card detection method, and the influence of age, sex, pregnancy history and blood transfusion history on irregular antibodies was analyzed. Results A total of 50 irregular antibody positive patients were found in 16 273patients, and the positive rate of irregular antibody was 0.31%. In patients of different ages, the highest positive rate was 0.37% in patients aged 41-60 years before blood transfusion, while the lowest positive rate was 0.18% in patients >80 years old. In patients of different genders, the positive rate of irregular antibody in female patients was higher than that in male patients, which was 0.36% and 0.23%, respectively. In patients with different blood transfusion history and pregnancy history, the positive rate of irregular antibodies in patients with blood transfusion history is higher than that in patients without blood transfusion history. In addition, the positive rate of irregular antibodies in patients with pregnancy history is higher than that in patients without pregnancy history. Conclusion The positive rate of irregular antibodies in patients before blood transfusion is high, among which the positive rate of irregular antibodies in patients aged 41-60 years, female patients, patients with blood transfusion history and pregnancy history is higher.Therefore, it is very necessary to screen irregular antibodies in such patients before blood transfusion.

关 键 词：不规则抗体 输血前 筛查价值 

分 类 号：R59[医药卫生—内科学]