围手术期口服营养补充对肥胖症患者行腹腔镜袖状胃切除术后短期疗效影响的前瞻性研究  

Influence of perioperative oral nutritional supplementation on short-term efficacy of laparoscopic sleeve gastrectomy for obesity patients:a prospective study

作　　者：张盛军 张娜[1] 程倩 陈启众[1] 邓莲 王磊[3] 俞永涛 陈申思 Zhang Shengjun;Zhang Na;Cheng Qian;Chen Qizhong;Deng Lian;Wang Lei;Yu Yongtao;Chen Shensi(Department of Nutrition,General Hospital of Ningxia Medical University,Yinchuan 750001,China;School of Public Health and Management,Ningxia Medical University,Yinchuan 750001,China;Department of Gastrointestinal Surgery,General Hospital of Ningxia Medical University,Yinchuan 750001,China)

机构地区：[1]宁夏医科大学总医院营养科,银川750001 [2]宁夏医科大学公共卫生与管理学院,银川750001 [3]宁夏医科大学总医院胃肠外科,银川750001

出　　处：《中华消化外科杂志》2022年第11期1432-1439,共8页Chinese Journal of Digestive Surgery

基　　金：宁夏自然科学基金(2021AAC03370);宁夏科技惠民计划(2020CMG03004)。

摘　　要：目的探讨围手术期口服营养补充对肥胖症患者行腹腔镜袖状胃切除术(LSG)后短期疗效的影响。方法采用前瞻性研究方法。选取2018年1月至2021年12月宁夏医科大学总医院收治的218例肥胖症行LSG患者的临床资料。患者围手术期行口服营养补充治疗设为试验组,行常规治疗设为对照组。观察指标:(1)入组患者分组情况。(2)术后及随访情况。(3)营养相关指标情况。(4)饮食依从性情况。(5)减重相关指标情况。采用电话、微信和门诊方式进行随访。患者出院后30 d随访1次,随访内容包括白蛋白(Alb)、血红蛋白(Hb)、饮食依从性情况和减重相关指标。随访时间截至2022年2月。正态分布的计量资料以x±s表示,组间比较采用独立样本t检验。偏态分布的计量资料以M(范围)表示,组间比较采用Mann‑Whitney U检验。计数资料以绝对数或百分比表示,组间比较采用χ^(2)检验。重复测量数据采用重复测量方差分析。等级资料比较采用秩和检验。结果(1)入组患者分组情况。筛选出符合条件的患者218例;男42例,女176例;年龄为(32±9)岁;体质量指数(BMI)为(39±7)kg/m^(2)。218例患者中,试验组和对照组各109例。试验组患者性别(男、女),年龄,BMI,术前Alb,术前Hb分别为17、92例,(33±9)岁,(39±7)kg/m^(2),(40.6±4.8)g/L,(141.7±13.9)g/L;对照组患者上述指标分别为25、84例,(31±8)岁,(39±8)kg/m^(2),(40.9±4.2)g/L,(142.9±9.7)g/L;两组患者上述指标比较,差异均无统计学意义(χ^(2)=1.89,t=-1.52、0.51、0.40、0.71,P>0.05)。(2)术后及随访情况。试验组患者首次住院时间、首次住院费用分别为(9.1±2.9)d、(3.6±0.5)万元;对照组患者上述指标分别为(11.6±3.7)d、(4.9±1.0)万元;两组患者上述指标比较,差异均有统计学意义(t=5.58,12.38,P<0.05)。218例患者中,119例获得随访,其中试验组62例、对照组57例。119例患者随访时间为31.0(25.0~38.0)d。218例患者中,14例发生�Objective To investigate the influence of perioperative oral nutritional supplementation on short-term efficacy of laparoscopic sleeve gastrectomy(LSG)for obesity patients.Methods The prospective study was conducted.The clinical data of 218 obesity patients who underwent LSG in the General Hospital of Ningxia Medical University from January 2018 to December 2021 were selected.Patients receiving perioperative oral nutritional supplementation were allocated into the experiment group,and patients receiving perioperative conventional treatment were allocated into the control group,respectively.Observation indicators:(1)grouping situations of the enrolled patients;(2)postoperative situations and follow-up;(3)nutrition related indicators;(4)dietary compliance;(5)weight loss related indicators.Follow-up was conducted using telephone interview,WeChat communication and outpatient examination to detect albumin(ALB),hemoglobin(HB),dietary compliance and weight loss related indicators of patients up to February 2022.Patients were followed up once every 30 days after discharge.Measurement data with normal distribution were represented as Mean±SD,and comparison between groups was conducted using the independent sample t test.Measurement data with skewed distribution were represented as M(range),and comparison between groups was conducted using the Mann-Whitney U test.Count data were described as absolute numbers or percentages,and comparison between groups was performed using the chi-square test.Repeated measurement data were analyzed using the repeated ANOVA.Comparison of ordinal data was analyzed using the rank sum test.Results(1)Grouping situations of the enrolled patients.A total of 218 patients were selected for eligibility.There were 42 males and 176 females,aged(32±9)years with body mass index(BMI)as(39±7)kg/m^(2).Of the 218 patients,there were 109 patients in the experiment group and 109 patients in the control group.Gender(male,female),age,BMI,preoperative albumin(Alb),preoperative hemoglobin(Hb)were 17,92,(33±9)y

关 键 词：肥胖症 减重手术 营养干预 再入院 营养状况 腹腔镜检查 

分 类 号：R656.61[医药卫生—外科学]