2种圆形微孔板内部流场的CFD数值模拟  

CFD numerical simulation of internal flow field of two circular micro plates

作　　者：朱建勇 刘秀敏[2] 陈吴西[3] 李德茂[3] ZHU Jian-yong;LIU Xiu-min;CHEN Wu-xi;LI De-mao(College of Bioengineering,Tianjin University of Science and Technology,Tianjin 300457,China;Research and Development Center of Food Engineering,Hebei Jiaotong Vocational and Technical College,Shijiazhuang 050035,Hebei Province,China;National Synthetic Biotechnology Innovation Center,Tianjin Institute of Industrial Biotechnology,Chinese Academy of Sciences,Tianjin 300308,China)

机构地区：[1]天津科技大学生物工程学院,天津300457 [2]河北交通职业技术学院粮食工程研发中心,河北石家庄050035 [3]中国科学院天津工业生物技术研究所国家合成生物技术创新中心,天津300308

出　　处：《化学工程》2023年第1期84-89,共6页Chemical Engineering(China)

基　　金：国家重点研发项目(2018YFA0902200);天津市合成生物提升行动计划(TSBICIP-KJGG-005)。

摘　　要：为改善96孔板传质率和剪切力低的情况,提出一种带挡板的96孔板模型。基于VOF模型和RNG k-ε模型结合建立了孔板内部的流体动力学模型,利用仿真软件FLUENT对其数值进行模拟。在不同转速下,对其气液交界面面积、气液比表面积、平均液膜传质系数和体积平均气液传质系数等传质相关系数和平均剪切应变率进行对比。模拟结果表明:在不同转速下,带挡板96孔板的体积平均传质系数和剪切应变率都要高于普通96孔板;并且考察了带挡板96孔板在特定转速下不同装液量对其传质性能的影响。模拟结果表明:随着装液量的增加带挡板96孔板的气液传质系数逐渐降低,得出66.56μL为最佳装液量。综上所述,带挡板96孔板有效提高了普通96孔板的传质性能,并为其提供了更好的剪切环境,为孔板的设计和优化提供了参考。A 96-well plate model with baffles was proposed to improve the low mass transfer efficiency and low sheer force of 96-well plate.Based on the combination of the VOF model and RNG k-εmodel,the fluid dynamics model inside the 96-well plate was established and the simulation software FLUENT was used to simulate its numerical value.The mass transfer correlation coefficients such as gas-liquid interface area,gas-liquid specific surface area,average liquid membrane mass transfer coefficient,volume gas-liquid mass transfer coefficient average and average shear strain rate were compared at different rotational speeds.The simulation results show that the volume mass transfer coefficient average and shear strain rate of 96-well plate with baffles are higher than those of the ordinary 96-well plates at different rotational speeds.Moreover,the influence of different filling volume on the mass transfer performance of 96-well plate with baffles at a specific speed was also investigated.The results show that with the increase of the liquid filling volume,the gas-liquid mass transfer coefficient of the 96-well plate with baffles gradually decreases at optimal loading volume of 66.56μL.In summary,adding baffles can help improve the mass transfer performance of ordinary 96-well plates,which can provide a better shearing environment for the fluid inside the orifice plate.This would be helpful to design and optimization for 96-well planes.

关 键 词：96孔板 计算流体力学 气液传质 剪切 

分 类 号：Q813.1[生物学—生物工程]