外阴血管肌纤维母细胞瘤复发1例报告及文献复习  

Recurrent vulvar angiomyofibroblastoma:A case report and literature review

作　　者：贾荣霞 周旭 石贽堃 包美静 王冠群 褚雨晴 金洋 林杨[1] JIA Rongxia;ZHOU Xu;SHI Zhikun;BAO Meijing;WANG Guanqun;CHU Yuqing;JIN Yang;LIN Yang(Department of Obstetrics and Gynecology,Second Hospital,Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院妇产科,吉林长春130041

出　　处：《吉林大学学报（医学版）》2023年第1期193-197,共5页Journal of Jilin University：Medicine Edition

基　　金：国家自然科学基金项目(81802613);吉林省卫健委科研项目(2020J039);吉林省财政厅科研项目(2019SCZT016,2020SCZT009)。

摘　　要：目的:探讨外阴血管肌纤维母细胞瘤(AMFB)复发患者的临床特征、诊断过程和治疗方法,旨在提高临床医生对该病的认识。方法:收集1例复发性外阴AMFB患者的临床资料、影像学检查结果、病理检查结果和免疫组织化学检测结果,分析上述资料并进行相关文献复习。结果:患者,女性,50岁,5年前因外阴肿物于当地医院行外阴肿物病灶切除术,术后病理提示AMFB。现因自觉外阴部肿物6个月,高度怀疑外阴AMFB复发入院。妇科检查,左侧大阴唇下方可见肿物凸起,表面皮肤完整,肿物深部凸向直肠,与肠管界限不清,大小约为5.0 cm×4.0 cm×4.0 cm,形态尚规则,界限尚清,活动性欠佳,无明显压痛,无溃破和皮损。浅表超声显示左侧大阴唇处可见范围约5.0 cm×4.0 cm×4.0 cm的稍低无回声光团,其内可见多处团状高回声;彩色多普勒血流显像(CDFI)示内部及周边可见血流信号。行外阴肿物切除术,结合术后病理和免疫组织化学诊断为外阴AMFB复发。结论:AMFB虽较少见复发及恶变,但应高度重视AMFB的术后随访,以减少复发并提高治愈率。Objective:To investigate the clinical characteristics,diagnosis procedure and treatment method of the patient with recurrent vulvar angiomyofibroblastoma(AMFB),and to improve the understanding of clinical doctors to this disease.Methods:The clinical data,imaging examination results,pathological examination results and immunohistochemical examination results of 1 patient with recurrent vulvar AMFB were collected;the above clinical data were analyzed,and the relevant literatures were reviewed.Results:A 50-year-old female patient underwent excision of vulvar mass 5 years ago in the local hospital for a vulvar mass,the postoperative pathology suggested AMFB.The patient was now admitted to the hospital due to a 6-month self-reported vaginal mass and a high degree of suspicion of recurrence of AMFB.The gynecological examination suggested a swelling under the labia major on the left side,with complete skin surface,deep protrusion towards the rectum and unclear boundary with the bowel;the size of tumor was about 5.0 cm×4.0 cm×4.0 cm,with regular shape,clear boundary,and poor activity,and there was no obvious tenderness,ulceration and skin lesion.Superficial ultrasound showed a slightly low anechoic light mass with a range of 5.0 cm×4.0 cm×4.0 cm at the left labia major,in which multiple mass hyperechoics were observed.Color Doppler flow imaging(CDFI)showed visible blood flow signals in and around the labia major.Conclusion:Although recurrence and malignancy of AMFB are rare,postoperative follow-up of AMFB should be given high priority to reduce the recurrence and increase the cure rate.

关 键 词：血管肌纤维母细胞瘤 外阴 免疫组织化学 复发 

分 类 号：R711.72[医药卫生—妇产科学]