中药大黄有效提取物大黄素诊治肿瘤的研究进展  

The Progress in Tumor Diagnosis and Treatment of Emodin:an Effective Extract of TCM Rhubarb

作　　者：张栖溶 张莹[1] ZHANG Qirong;ZHANG Ying(Tianjin University of Traditional Chinese Medicine,First Teaching Hospital of Tianjin University ofTraditional Chinese Medicine,National Clinical Research Center for Chinese MedicineAcupuncture and Moxibustion,Tianjin 300381,China)

机构地区：[1]天津中医药大学,天津中医药大学第一附属医院,国家中医针灸临床医学研究中心,天津300381

出　　处：《标记免疫分析与临床》2022年第10期1784-1788,共5页Labeled Immunoassays and Clinical Medicine

基　　金：国家自然科学基金资助项目(编号:82104553)。

摘　　要：中药大黄是中医抗肿瘤的常用药物之一,它的有效提取物有芦荟大黄素、大黄素、大黄酸、大黄多糖等等。大黄素具有抗肿瘤、抗炎、镇痛、保护器官、降脂、抗抑郁、抑制心肌纤维化、抗脊髓水肿、抑菌等作用。本文回顾了近3年国内外有关大黄素抗肿瘤作用的研究,包括其单用、联合以及逆转耐药等方面,提示了其具有潜在的临床应用前景。Traditional Chinese medicine rhubarb is one of the commonly used anti-tumor drugs in traditional Chinese medicine.Its effective extracts include aloe emodin,emodin,rhein acid,rhubarb polysaccharide and more.Emodin has the effects of anti-tumor,anti-inflammatory,analgesic,organ protection,lipid-lowering,antidepressant,myocardial fibrosis inhibition,spinal cord edema inhibition,and antibacterial.This paper reviews previous studies on the anti-tumor effect of emodin at home and abroad in the past three years,including its single use,combination and reversal of drug resistance,suggesting its potential clinical application prospect.

关 键 词：大黄素 抗肿瘤 综述 

分 类 号：R285[医药卫生—中药学]